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Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.

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Title: Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
Authors: Liang YL; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Belousoff MJ; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Zhao P; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Koole C; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Fletcher MM; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Truong TT; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Julita V; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Christopoulos G; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Xu HE; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA., Zhang Y; Departments of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China., Khoshouei M; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany., Christopoulos A; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Danev R; Graduate School of Medicine, University of Tokyo, S402, 7-3-1 Hongo, Bunkyo-ku, 113-0033 Tokyo, Japan. Electronic address: rado@m.u-tokyo.ac.jp., Sexton PM; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: patrick.sexton@monash.edu., Wootten D; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: denise.wootten@monash.edu.
Source: Molecular cell [Mol Cell] 2020 Feb 06; Vol. 77 (3), pp. 656-668.e5. Date of Electronic Publication: 2020 Jan 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
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  Data: <searchLink fieldCode="AU" term="%22Liang+YL%22">Liang YL</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Belousoff+MJ%22">Belousoff MJ</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Zhao+P%22">Zhao P</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Koole+C%22">Koole C</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Fletcher+MM%22">Fletcher MM</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Truong+TT%22">Truong TT</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Julita+V%22">Julita V</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Christopoulos+G%22">Christopoulos G</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Xu+HE%22">Xu HE</searchLink>; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Departments of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Khoshouei+M%22">Khoshouei M</searchLink>; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Christopoulos+A%22">Christopoulos A</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Danev+R%22">Danev R</searchLink>; Graduate School of Medicine, University of Tokyo, S402, 7-3-1 Hongo, Bunkyo-ku, 113-0033 Tokyo, Japan. Electronic address: rado@m.u-tokyo.ac.jp.<br /><searchLink fieldCode="AU" term="%22Sexton+PM%22">Sexton PM</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: patrick.sexton@monash.edu.<br /><searchLink fieldCode="AU" term="%22Wootten+D%22">Wootten D</searchLink>; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: denise.wootten@monash.edu.
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