Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.

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Title: Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.
Authors: Durrant CS; John van Geest Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK.; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.; Centre for Discovery Brain Sciences, University of Edinburgh, 1 George Square, Edinburgh, EH8 9JZ, UK., Ruscher K; Laboratory for Experimental Brain Research, Department of Clinical Sciences, Lund University, SE, Lund, Sweden.; Lund Brain Injury Laboratory for Neurosurgical Research, Department of Clinical Sciences, Lund University, Lund, Sweden., Sheppard O; John van Geest Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK., Coleman MP; John van Geest Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK. mc469@cam.ac.uk.; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK. mc469@cam.ac.uk.; John van Geest Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK. mc469@cam.ac.uk., Özen I; John van Geest Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK. ilknur.ozen@med.lu.se.; Lund Brain Injury Laboratory for Neurosurgical Research, Department of Clinical Sciences, Lund University, Lund, Sweden. ilknur.ozen@med.lu.se.; Lund Brain Injury Laboratory for Neurosurgical Research, Wallenberg Neuroscience Center, Lund University, BMC A13, 221 84, Lund, Sweden. ilknur.ozen@med.lu.se.
Source: Cell death & disease [Cell Death Dis] 2020 Feb 06; Vol. 11 (2), pp. 98. Date of Electronic Publication: 2020 Feb 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-020-2288-4