Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
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| Title: | Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module. |
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| Authors: | Di Magno L; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161 Rome, Italy., Manni S; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Di Pastena F; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Coni S; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Macone A; Department of Biochemical Sciences A. Rossi Fanelli, Sapienza University of Rome, 00185 Rome, Italy., Cairoli S; Division of Metabolism and Research Unit of metabolic Biochemistry, Children's Hospital and Research Institute Bambino Gesù IRCCS, 00146 Rome, Italy., Sambucci M; IRCCS Santa Lucia Foundation, Neuroimmunology Unit, 00143 Rome, Italy., Infante P; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161 Rome, Italy., Moretti M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Petroni M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Nicoletti C; Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Unit of Histology and Medical Embryology, Sapienza University of Rome, 00161 Rome, Italy., Capalbo C; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., De Smaele E; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy., Di Marcotullio L; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161 Rome, Italy., Giannini G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Battistini L; IRCCS Santa Lucia Foundation, Neuroimmunology Unit, 00143 Rome, Italy., Goffredo BM; Division of Metabolism and Research Unit of metabolic Biochemistry, Children's Hospital and Research Institute Bambino Gesù IRCCS, 00146 Rome, Italy., Iorio E; Core Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy., Agostinelli E; Department of Biochemical Sciences A. Rossi Fanelli, Sapienza University of Rome, 00185 Rome, Italy; International Polyamines Foundation-ONLUS, 00159 Rome, Italy., Maroder M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161 Rome, Italy; International Polyamines Foundation-ONLUS, 00159 Rome, Italy. Electronic address: gianluca.canettieri@uniroma1.it. |
| Source: | Cell reports [Cell Rep] 2020 Feb 11; Vol. 30 (6), pp. 1735-1752.e7. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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