Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases.

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Title: Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases.
Authors: McGregor NGS; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York YO10 5DD, U.K., Artola M; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands., Nin-Hill A; Departament de Quı́mica Inorgànica i Orgànica (Secció de Quı́mica Orgànica) & Institut de Quı́mica Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain., Linzel D; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands., Haon M; INRA, Aix Marseille University, Biodiversité et Biotechnologie Fongiques (BBF), UMR1163, F-13009 Marseille, France., Reijngoud J; Molecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands., Ram A; Molecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands., Rosso MN; INRA, Aix Marseille University, Biodiversité et Biotechnologie Fongiques (BBF), UMR1163, F-13009 Marseille, France., van der Marel GA; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands., Codée JDC; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands., van Wezel GP; Molecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands., Berrin JG; INRA, Aix Marseille University, Biodiversité et Biotechnologie Fongiques (BBF), UMR1163, F-13009 Marseille, France., Rovira C; Departament de Quı́mica Inorgànica i Orgànica (Secció de Quı́mica Orgànica) & Institut de Quı́mica Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08020 Barcelona, Spain., Overkleeft HS; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands., Davies GJ; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York YO10 5DD, U.K.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2020 Mar 11; Vol. 142 (10), pp. 4648-4662. Date of Electronic Publication: 2020 Feb 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-5126
DOI:10.1021/jacs.9b11351