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Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue.

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Title: Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue.
Authors: Kohajda Z; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Tóth N; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Szlovák J; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Loewe A; Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Bitay G; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Gazdag P; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Prorok J; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Jost N; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Levijoki J; Orion Pharma, Espoo, Finland., Pollesello P; Orion Pharma, Espoo, Finland., Papp JG; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Varró A; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary., Nagy N; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Source: Frontiers in pharmacology [Front Pharmacol] 2020 Jan 29; Vol. 10, pp. 1632. Date of Electronic Publication: 2020 Jan 29 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Novel Na<superscript>+</superscript>/Ca<superscript>2+</superscript> Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na<superscript>+</superscript>/Ca<superscript>2+</superscript> Exchanger in Pacemaking of Rabbit Sinus Node Tissue.
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  Data: <searchLink fieldCode="AU" term="%22Kohajda+Z%22">Kohajda Z</searchLink>; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Tóth+N%22">Tóth N</searchLink>; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Szlovák+J%22">Szlovák J</searchLink>; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Loewe+A%22">Loewe A</searchLink>; Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Bitay+G%22">Bitay G</searchLink>; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Gazdag+P%22">Gazdag P</searchLink>; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Prorok+J%22">Prorok J</searchLink>; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Jost+N%22">Jost N</searchLink>; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Levijoki+J%22">Levijoki J</searchLink>; Orion Pharma, Espoo, Finland.<br /><searchLink fieldCode="AU" term="%22Pollesello+P%22">Pollesello P</searchLink>; Orion Pharma, Espoo, Finland.<br /><searchLink fieldCode="AU" term="%22Papp+JG%22">Papp JG</searchLink>; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Varró+A%22">Varró A</searchLink>; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Nagy+N%22">Nagy N</searchLink>; MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary.
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