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Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.

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Title: Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.
Authors: Heck CJS; Department of Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States., Seneviratne HK; Department of Medicine, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States., Bumpus NN; Department of Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.; Department of Medicine, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2020 Jun 25; Vol. 63 (12), pp. 6561-6574. Date of Electronic Publication: 2020 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.
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  Data: <searchLink fieldCode="AU" term="%22Heck+CJS%22">Heck CJS</searchLink>; Department of Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.<br /><searchLink fieldCode="AU" term="%22Seneviratne+HK%22">Seneviratne HK</searchLink>; Department of Medicine, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.<br /><searchLink fieldCode="AU" term="%22Bumpus+NN%22">Bumpus NN</searchLink>; Department of Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.; Department of Medicine, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2020 Jun 25; Vol. 63 (12), pp. 6561-6574. <i>Date of Electronic Publication: </i>2020 Feb 27.
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        Value: 10.1021/acs.jmedchem.9b01990
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        Text: English
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        StartPage: 6561
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      – TitleFull: Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.
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            NameFull: Heck CJS
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            NameFull: Seneviratne HK
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              Text: 2020 Jun 25
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              Y: 2020
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