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Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.

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Title: Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
Authors: Weisel FJ; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. fweisel@pitt.edu., Mullett SJ; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA., Elsner RA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Menk AV; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA., Trivedi N; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Luo W; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Wikenheiser D; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Hawse WF; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Chikina M; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Smita S; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Conter LJ; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Joachim SM; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Wendell SG; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Jurczak MJ; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Winkler TH; Division of Genetics, Department of Biology, Nikolaus-Fiebiger-Center for Molecular Medicine, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany., Delgoffe GM; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA., Shlomchik MJ; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. mshlomch@pitt.edu.
Source: Nature immunology [Nat Immunol] 2020 Mar; Vol. 21 (3), pp. 331-342. Date of Electronic Publication: 2020 Feb 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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  Data: Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
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  Data: <searchLink fieldCode="AU" term="%22Weisel+FJ%22">Weisel FJ</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. fweisel@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Mullett+SJ%22">Mullett SJ</searchLink>; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Elsner+RA%22">Elsner RA</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Menk+AV%22">Menk AV</searchLink>; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Trivedi+N%22">Trivedi N</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Luo+W%22">Luo W</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wikenheiser+D%22">Wikenheiser D</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hawse+WF%22">Hawse WF</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chikina+M%22">Chikina M</searchLink>; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Smita+S%22">Smita S</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Conter+LJ%22">Conter LJ</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Joachim+SM%22">Joachim SM</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wendell+SG%22">Wendell SG</searchLink>; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Jurczak+MJ%22">Jurczak MJ</searchLink>; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Winkler+TH%22">Winkler TH</searchLink>; Division of Genetics, Department of Biology, Nikolaus-Fiebiger-Center for Molecular Medicine, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Delgoffe+GM%22">Delgoffe GM</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shlomchik+MJ%22">Shlomchik MJ</searchLink>; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. mshlomch@pitt.edu.
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