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Immune checkpoint modulation enhances HIV-1 antibody induction.

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Title: Immune checkpoint modulation enhances HIV-1 antibody induction.
Authors: Bradley T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. tcbradley@cmh.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA. tcbradley@cmh.edu.; Center for Pediatric Genomic Medicine, Children's Mercy Kansas City, Kansas City, MO, 64108, USA. tcbradley@cmh.edu.; Department of Pediatrics, UMKC School of Medicine, Kansas City, MO, 64108, USA. tcbradley@cmh.edu., Kuraoka M; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Yeh CH; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Tian M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Genetic, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, 02115, USA., Chen H; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Genetic, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, 02115, USA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892, USA., Cheng C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892, USA., Ellebedy AH; Emory Vaccine Center, Emory University, Atlanta, GA, 30317, USA.; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, 63110, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Bowman CM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Bouton-Verville H; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Santra S; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA., Wiehe K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Lewis MG; BIOQUAL, Inc, Rockville, MD, 20850, USA., Ogbe A; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7FZ, UK., Borrow P; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7FZ, UK., Montefiori D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University, Durham, NC, 27710, USA., Bonsignori M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Anthony Moody M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, 27710, USA., Verkoczy L; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; San Diego Biomedical Research Institute, San Diego, CA, 92121, USA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University, Durham, NC, 27710, USA., Ahmed R; Emory Vaccine Center, Emory University, Atlanta, GA, 30317, USA., Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892, USA., Kelsoe G; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Alt FW; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Genetic, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, 02115, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Barton.haynes@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA. Barton.haynes@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. Barton.haynes@duke.edu.
Source: Nature communications [Nat Commun] 2020 Feb 19; Vol. 11 (1), pp. 948. Date of Electronic Publication: 2020 Feb 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Immune checkpoint modulation enhances HIV-1 antibody induction.
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  Data: <searchLink fieldCode="AU" term="%22Bradley+T%22">Bradley T</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. tcbradley@cmh.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA. tcbradley@cmh.edu.; Center for Pediatric Genomic Medicine, Children's Mercy Kansas City, Kansas City, MO, 64108, USA. tcbradley@cmh.edu.; Department of Pediatrics, UMKC School of Medicine, Kansas City, MO, 64108, USA. tcbradley@cmh.edu.<br /><searchLink fieldCode="AU" term="%22Kuraoka+M%22">Kuraoka M</searchLink>; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+CH%22">Yeh CH</searchLink>; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tian+M%22">Tian M</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Genetic, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; 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Emory Vaccine Center, Emory University, Atlanta, GA, 30317, USA.<br /><searchLink fieldCode="AU" term="%22Mascola+JR%22">Mascola JR</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Kelsoe+G%22">Kelsoe G</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Alt+FW%22">Alt FW</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Department of Genetic, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Haynes+BF%22">Haynes BF</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. 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