Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group.
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| Title: | Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group. |
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| Authors: | Herishanu Y; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel., Shaulov A; Hadassah Hebrew University Medical Center, Jerusalem, Israel., Fineman R; Department of Hematology, Rambam Health Care Campus, Haifa, Israel., Bašić-Kinda S; University Hospital Centre Zagreb, Zagreb, Croatia., Aviv A; Department of Hematology, HaEmek Medical Center, Afula, Israel.; Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel., Wasik-Szczepanek E; Department of Hematooncology, and Bone Marrow Transplantation Medical University, Lublin, Poland., Jaksic O; Dubrava University Hospital, Zagreb, Croatia., Zdrenghea M; Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania., Greenbaum U; Ben-Gurion University, Soroka University Medical Center, Beer Sheva, Israel., Mandac I; Clinical Hospital Merkur, Zagreb, Croatia., Simkovic M; University Hospital and Medical School Hradec Kralove, Hradec Kralove, Czech Republic., Morawska M; St. John's Cancer Center, Lublin, Poland., Benjamini O; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.; Hematology Division, Chaim Sheba Medical Center, Ramat Gan, Israel., Spacek M; Charles University and General Hospital in Prague, Prague, Czech Republic., Nemets A; Barzilai University Medical Center, Ashkelon, Israel., Bairey O; Rabin Medical Center, Beilinson Hospital; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Trentin L; Hematology Unit, University of Padua, Padua, Italy., Ruchlemer R; Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel., Laurenti L; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Stanca Ciocan O; Coltea Clinical Hospital, Bucharest, Romania., Doubek M; Department of Internal Medicine-Hematology and Oncology, Medical Faculty of Masaryk University and University Hospital Brno, Brno, Czech Republic., Shvidel L; Department of Hematology, Kaplan Medical Center, Rehovot, Israel.; Hebrew University of Jerusalem, Jerusalem, Israel., Dali N; Ziv Medical Center, Safed, Israel., Mirás F; Hospital 12 de Octubre, Madrid, Spain., De Meûter A; Institut Jules Bordet, Brussels, Belgium., Dimou M; Hematology Section - 1st Department Of Propaedeutic Internal Medicine, Laikon Hospital, Athens, Greece., Mauro FR; Hematology, Department of Translational and Precision Medicine, Sapienza University, Policlinico Umberto I, Rome, Italy., Coscia M; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Bumbea H; Emergency University Clinical Hospital, Bucharest, Romania., Szász R; Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Tadmor T; Hematology, Bnai Zion Medical Center, Haifa, Israel., Gutwein O; Assaf Ha'Rofeh, Tsrifin, Israel., Gentile M; Hematology Unit and Biotechnology Research Unit, A.O. of Cosenza, Cosenza, Italy., Scarfò L; Division of Experimental Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Tedeschi A; Department of Haematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Sportoletti P; Institute of Hematology and Center for Hemato-Oncological Research, Ospedale S. Maria della Misericordia, University of Perugia, Perugia, Italy., Gimeno Vázquez E; Hospital del Mar, Barcelona, Spain., Marquet J; Hematology and Hemotherapy, Hospital Universitario Ramón y Cajal, Madrid, Spain., Assouline S; Division of Hematology, Jewish General Hospital, Montreal, Quebec, Canada., Papaioannou M; First Department of Internal Medicine, Division of Haematology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Braester A; Galilee Medical Center, Nahariya, Israel., Levato L; Department Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy., Gregor M; Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland., Rigolin GM; Hematology Section, Department of Medical Sciences, University of Ferrara-Azienda Ospedaliera-Universitaria di Ferrara, University of Ferrara, Ferrara, Italy., Loscertales J; IIS-IP, Hospital Universitario de La Princesa, Madrid, Spain., Medina Perez A; Hospital Costa del Sol, Marbella, Spain., Nijziel MR; Maxima Medical Center Eindhoven/Veldhoven, Eindhoven, Netherlands., Popov VM; Hematology, Colentina Clinical Hospital, Bucharest, Romania., Collado R; Hospital General Universitario, Valencia, Spain., Slavutsky I; Hospital Alvarez, Buenos Aires, Argentina., Itchaki G; Rabin Medical Center, Beilinson Hospital; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Ringelstein S; Department of Hematology, Rambam Health Care Campus, Haifa, Israel., Goldschmidt N; Hadassah Hebrew University Medical Center, Jerusalem, Israel., Perry C; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel., Levi S; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Polliack A; Hadassah Hebrew University Medical Center, Jerusalem, Israel., Ghia P; Division of Experimental Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy. |
| Source: | American journal of hematology [Am J Hematol] 2020 Jun; Vol. 95 (6), pp. 604-611. Date of Electronic Publication: 2020 Mar 14. |
| Publication Type: | Journal Article; Multicenter Study; Observational Study |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32096887 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Herishanu+Y%22">Herishanu Y</searchLink>; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Shaulov+A%22">Shaulov A</searchLink>; Hadassah Hebrew University Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Fineman+R%22">Fineman R</searchLink>; Department of Hematology, Rambam Health Care Campus, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Bašić-Kinda+S%22">Bašić-Kinda S</searchLink>; University Hospital Centre Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Aviv+A%22">Aviv A</searchLink>; Department of Hematology, HaEmek Medical Center, Afula, Israel.; Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Wasik-Szczepanek+E%22">Wasik-Szczepanek E</searchLink>; Department of Hematooncology, and Bone Marrow Transplantation Medical University, Lublin, Poland.<br /><searchLink fieldCode="AU" term="%22Jaksic+O%22">Jaksic O</searchLink>; Dubrava University Hospital, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Zdrenghea+M%22">Zdrenghea M</searchLink>; Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Greenbaum+U%22">Greenbaum U</searchLink>; Ben-Gurion University, Soroka University Medical Center, Beer Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Mandac+I%22">Mandac I</searchLink>; Clinical Hospital Merkur, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Simkovic+M%22">Simkovic M</searchLink>; University Hospital and Medical School Hradec Kralove, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Morawska+M%22">Morawska M</searchLink>; St. John's Cancer Center, Lublin, Poland.<br /><searchLink fieldCode="AU" term="%22Benjamini+O%22">Benjamini O</searchLink>; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.; Hematology Division, Chaim Sheba Medical Center, Ramat Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Spacek+M%22">Spacek M</searchLink>; Charles University and General Hospital in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Nemets+A%22">Nemets A</searchLink>; Barzilai University Medical Center, Ashkelon, Israel.<br /><searchLink fieldCode="AU" term="%22Bairey+O%22">Bairey O</searchLink>; Rabin Medical Center, Beilinson Hospital; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Trentin+L%22">Trentin L</searchLink>; Hematology Unit, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Ruchlemer+R%22">Ruchlemer R</searchLink>; Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Laurenti+L%22">Laurenti L</searchLink>; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stanca+Ciocan+O%22">Stanca Ciocan O</searchLink>; Coltea Clinical Hospital, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Doubek+M%22">Doubek M</searchLink>; Department of Internal Medicine-Hematology and Oncology, Medical Faculty of Masaryk University and University Hospital Brno, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Shvidel+L%22">Shvidel L</searchLink>; Department of Hematology, Kaplan Medical Center, Rehovot, Israel.; Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Dali+N%22">Dali N</searchLink>; Ziv Medical Center, Safed, Israel.<br /><searchLink fieldCode="AU" term="%22Mirás+F%22">Mirás F</searchLink>; Hospital 12 de Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22De+Meûter+A%22">De Meûter A</searchLink>; Institut Jules Bordet, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Dimou+M%22">Dimou M</searchLink>; Hematology Section - 1st Department Of Propaedeutic Internal Medicine, Laikon Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Mauro+FR%22">Mauro FR</searchLink>; Hematology, Department of Translational and Precision Medicine, Sapienza University, Policlinico Umberto I, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Coscia+M%22">Coscia M</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Bumbea+H%22">Bumbea H</searchLink>; Emergency University Clinical Hospital, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Szász+R%22">Szász R</searchLink>; Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.<br /><searchLink fieldCode="AU" term="%22Tadmor+T%22">Tadmor T</searchLink>; Hematology, Bnai Zion Medical Center, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Gutwein+O%22">Gutwein O</searchLink>; Assaf Ha'Rofeh, Tsrifin, Israel.<br /><searchLink fieldCode="AU" term="%22Gentile+M%22">Gentile M</searchLink>; Hematology Unit and Biotechnology Research Unit, A.O. of Cosenza, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Scarfò+L%22">Scarfò L</searchLink>; Division of Experimental Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tedeschi+A%22">Tedeschi A</searchLink>; Department of Haematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sportoletti+P%22">Sportoletti P</searchLink>; Institute of Hematology and Center for Hemato-Oncological Research, Ospedale S. Maria della Misericordia, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Gimeno+Vázquez+E%22">Gimeno Vázquez E</searchLink>; Hospital del Mar, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Marquet+J%22">Marquet J</searchLink>; Hematology and Hemotherapy, Hospital Universitario Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Assouline+S%22">Assouline S</searchLink>; Division of Hematology, Jewish General Hospital, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Papaioannou+M%22">Papaioannou M</searchLink>; First Department of Internal Medicine, Division of Haematology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Braester+A%22">Braester A</searchLink>; Galilee Medical Center, Nahariya, Israel.<br /><searchLink fieldCode="AU" term="%22Levato+L%22">Levato L</searchLink>; Department Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Gregor+M%22">Gregor M</searchLink>; Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rigolin+GM%22">Rigolin GM</searchLink>; Hematology Section, Department of Medical Sciences, University of Ferrara-Azienda Ospedaliera-Universitaria di Ferrara, University of Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Loscertales+J%22">Loscertales J</searchLink>; IIS-IP, Hospital Universitario de La Princesa, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Medina+Perez+A%22">Medina Perez A</searchLink>; Hospital Costa del Sol, Marbella, Spain.<br /><searchLink fieldCode="AU" term="%22Nijziel+MR%22">Nijziel MR</searchLink>; Maxima Medical Center Eindhoven/Veldhoven, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Popov+VM%22">Popov VM</searchLink>; Hematology, Colentina Clinical Hospital, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Collado+R%22">Collado R</searchLink>; Hospital General Universitario, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Slavutsky+I%22">Slavutsky I</searchLink>; Hospital Alvarez, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Itchaki+G%22">Itchaki G</searchLink>; Rabin Medical Center, Beilinson Hospital; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Ringelstein+S%22">Ringelstein S</searchLink>; Department of Hematology, Rambam Health Care Campus, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Goldschmidt+N%22">Goldschmidt N</searchLink>; Hadassah Hebrew University Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Perry+C%22">Perry C</searchLink>; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Levi+S%22">Levi S</searchLink>; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Polliack+A%22">Polliack A</searchLink>; Hadassah Hebrew University Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Ghia+P%22">Ghia P</searchLink>; Division of Experimental Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227610369%22">American journal of hematology</searchLink> [Am J Hematol] 2020 Jun; Vol. 95 (6), pp. 604-611. <i>Date of Electronic Publication: </i>2020 Mar 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Observational Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7610369 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203618609%22">03618609 </searchLink><i>NLM ISO Abbreviation: </i>Am J Hematol <i>Subsets: </i>MEDLINE |
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