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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.

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Title: Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
Authors: Tang B; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Frasinyuk MS; V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv 02094, Ukraine.; National University of Food Technologies, Kyiv 01601, Ukraine., Chikwana VM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Mahalingan KK; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Morgan CA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Segvich DM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Bondarenko SP; National University of Food Technologies, Kyiv 01601, Ukraine., Mrug GP; V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv 02094, Ukraine.; National University of Food Technologies, Kyiv 01601, Ukraine., Wyrebek P; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington 40506, Kentucky, United States.; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington 40536, Kentucky, United States., Watt DS; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington 40506, Kentucky, United States.; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington 40536, Kentucky, United States.; Lucille Parker Markey Cancer Center, University of Kentucky, Lexington 40536, Kentucky, United States., DePaoli-Roach AA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Roach PJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States., Hurley TD; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2020 Apr 09; Vol. 63 (7), pp. 3538-3551. Date of Electronic Publication: 2020 Mar 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
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  Data: <searchLink fieldCode="AU" term="%22Tang+B%22">Tang B</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Frasinyuk+MS%22">Frasinyuk MS</searchLink>; V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv 02094, Ukraine.; National University of Food Technologies, Kyiv 01601, Ukraine.<br /><searchLink fieldCode="AU" term="%22Chikwana+VM%22">Chikwana VM</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Mahalingan+KK%22">Mahalingan KK</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Morgan+CA%22">Morgan CA</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Segvich+DM%22">Segvich DM</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Bondarenko+SP%22">Bondarenko SP</searchLink>; National University of Food Technologies, Kyiv 01601, Ukraine.<br /><searchLink fieldCode="AU" term="%22Mrug+GP%22">Mrug GP</searchLink>; V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv 02094, Ukraine.; National University of Food Technologies, Kyiv 01601, Ukraine.<br /><searchLink fieldCode="AU" term="%22Wyrebek+P%22">Wyrebek P</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington 40506, Kentucky, United States.; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington 40536, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Watt+DS%22">Watt DS</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington 40506, Kentucky, United States.; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington 40536, Kentucky, United States.; Lucille Parker Markey Cancer Center, University of Kentucky, Lexington 40536, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22DePaoli-Roach+AA%22">DePaoli-Roach AA</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Roach+PJ%22">Roach PJ</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Hurley+TD%22">Hurley TD</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202, Indiana, United States.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2020 Apr 09; Vol. 63 (7), pp. 3538-3551. <i>Date of Electronic Publication: </i>2020 Mar 23.
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        Value: 10.1021/acs.jmedchem.9b01851
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              Text: 2020 Apr 09
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