Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.

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Title: Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.
Authors: Bajpai R; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Sharma A; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Achreja A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA., Edgar CL; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Wei C; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Siddiqa AA; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Gupta VA; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Matulis SM; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., McBrayer SK; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA., Mittal A; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA., Rupji M; Department of Biostatistics and Bioinformatics Shared Resource, Winship Cancer Institute, Emory University, Atlanta, GA, USA., Barwick BG; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Lonial S; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Nooka AK; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Boise LH; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA., Nagrath D; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA., Shanmugam M; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA. mala.shan@emory.edu.
Source: Nature communications [Nat Commun] 2020 Mar 06; Vol. 11 (1), pp. 1228. Date of Electronic Publication: 2020 Mar 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.
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  Data: <searchLink fieldCode="AU" term="%22Bajpai+R%22">Bajpai R</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Achreja+A%22">Achreja A</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Edgar+CL%22">Edgar CL</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Wei+C%22">Wei C</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Siddiqa+AA%22">Siddiqa AA</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+VA%22">Gupta VA</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Matulis+SM%22">Matulis SM</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22McBrayer+SK%22">McBrayer SK</searchLink>; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mittal+A%22">Mittal A</searchLink>; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Rupji+M%22">Rupji M</searchLink>; Department of Biostatistics and Bioinformatics Shared Resource, Winship Cancer Institute, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Barwick+BG%22">Barwick BG</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Lonial+S%22">Lonial S</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Nooka+AK%22">Nooka AK</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Boise+LH%22">Boise LH</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Nagrath+D%22">Nagrath D</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Shanmugam+M%22">Shanmugam M</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA, USA. mala.shan@emory.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2020 Mar 06; Vol. 11 (1), pp. 1228. <i>Date of Electronic Publication: </i>2020 Mar 06.
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