Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
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| Title: | Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features. |
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| Authors: | Ray JP; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., de Boer CG; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA., Lareau CA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA., Kanai M; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.; Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, 02115, USA., Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA., Tewhey R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, 02138, USA., Ludwig LS; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Reilly SK; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, 02138, USA., Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Harvard Society of Fellows, Harvard University, Cambridge, MA, 02138, USA., Issner R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Finucane HK; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Howard Hughes Medical Institute, Cambridge, MA, 02142, USA. aregev@broadinstitute.org., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. nhacohen@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, 02114, USA. nhacohen@mgh.harvard.edu. |
| Source: | Nature communications [Nat Commun] 2020 Mar 06; Vol. 11 (1), pp. 1237. Date of Electronic Publication: 2020 Mar 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-15022-4 |
