Full-length human GLP-1 receptor structure without orthosteric ligands.
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| Title: | Full-length human GLP-1 receptor structure without orthosteric ligands. |
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| Authors: | Wu F; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Yang L; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Hang K; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Laursen M; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Wu L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Han GW; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA., Ren Q; Novo Nordisk Research Center, Beijing, China., Roed NK; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Lin G; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Hanson MA; GPCR Consortium, San Marcos, California, USA., Jiang H; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Wang MW; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, Fudan University, Shanghai, China., Reedtz-Runge S; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Song G; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. gjsong@bio.ecnu.edu.cn., Stevens RC; iHuman Institute, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA. stevens@shanghaitech.edu.cn. |
| Source: | Nature communications [Nat Commun] 2020 Mar 09; Vol. 11 (1), pp. 1272. Date of Electronic Publication: 2020 Mar 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-14934-5 |
