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Full-length human GLP-1 receptor structure without orthosteric ligands.

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Title: Full-length human GLP-1 receptor structure without orthosteric ligands.
Authors: Wu F; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Yang L; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Hang K; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Laursen M; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Wu L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Han GW; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA., Ren Q; Novo Nordisk Research Center, Beijing, China., Roed NK; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Lin G; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Hanson MA; GPCR Consortium, San Marcos, California, USA., Jiang H; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Wang MW; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, Fudan University, Shanghai, China., Reedtz-Runge S; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark., Song G; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. gjsong@bio.ecnu.edu.cn., Stevens RC; iHuman Institute, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA. stevens@shanghaitech.edu.cn.
Source: Nature communications [Nat Commun] 2020 Mar 09; Vol. 11 (1), pp. 1272. Date of Electronic Publication: 2020 Mar 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Full-length human GLP-1 receptor structure without orthosteric ligands.
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  Data: <searchLink fieldCode="AU" term="%22Wu+F%22">Wu F</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Hang+K%22">Hang K</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Laursen+M%22">Laursen M</searchLink>; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Han+GW%22">Han GW</searchLink>; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Ren+Q%22">Ren Q</searchLink>; Novo Nordisk Research Center, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Roed+NK%22">Roed NK</searchLink>; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lin+G%22">Lin G</searchLink>; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Hanson+MA%22">Hanson MA</searchLink>; GPCR Consortium, San Marcos, California, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+MW%22">Wang MW</searchLink>; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Reedtz-Runge+S%22">Reedtz-Runge S</searchLink>; Novo Nordisk A/S, Novo Nordisk Park, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Song+G%22">Song G</searchLink>; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. gjsong@bio.ecnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Stevens+RC%22">Stevens RC</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. stevens@shanghaitech.edu.cn.; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, California, USA. stevens@shanghaitech.edu.cn.
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