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Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.

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Title: Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.
Authors: Ali MK; Division of Pulmonary and Critical Care Medicine, Stanford University, Stanford, CA, USA.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Kim RY; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia., Brown AC; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Mayall JR; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Karim R; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Pinkerton JW; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Respiratory Pharmacology and Toxicology Group, National Heart and Lung Institute, Imperial College London, London, UK., Liu G; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia., Martin KL; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Starkey MR; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Dept of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, Australia., Pillar AL; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Donovan C; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia., Pathinayake PS; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, Australia., Carroll OR; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Trinder D; Medical School, Harry Perkins Medical Research Institute, University of Western Australia, Fiona Stanley Hospital, Perth, Australia., Tay HL; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Badi YE; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK., Kermani NZ; Data Science Institute, Dept of Computing, Imperial College London, London, UK., Guo YK; Data Science Institute, Dept of Computing, Imperial College London, London, UK., Aryal R; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Mumby S; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK., Pavlidis S; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK., Adcock IM; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK., Weaver J; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Xenaki D; Woolcock Institute of Medical Research, University of Sydney and School of Life Sciences, University of Technology Sydney, Sydney, Australia., Oliver BG; Woolcock Institute of Medical Research, University of Sydney and School of Life Sciences, University of Technology Sydney, Sydney, Australia., Holliday EG; Hunter Medical Research Institute, New Lambton, Australia.; School of Medicine and Public Health, University of Newcastle, Callaghan, Australia., Foster PS; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Wark PA; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Dept of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, Australia., Johnstone DM; Discipline of Physiology and Bosch Institute, University of Sydney, Sydney, Australia., Milward EA; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Hansbro PM; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia.; These authors contributed equally., Horvat JC; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; These authors contributed equally.
Source: The European respiratory journal [Eur Respir J] 2020 Apr 23; Vol. 55 (4). Date of Electronic Publication: 2020 Apr 23 (Print Publication: 2020).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.
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  Data: <searchLink fieldCode="AU" term="%22Ali+MK%22">Ali MK</searchLink>; Division of Pulmonary and Critical Care Medicine, Stanford University, Stanford, CA, USA.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Kim+RY%22">Kim RY</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+AC%22">Brown AC</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Mayall+JR%22">Mayall JR</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Karim+R%22">Karim R</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Pinkerton+JW%22">Pinkerton JW</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Respiratory Pharmacology and Toxicology Group, National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Martin+KL%22">Martin KL</searchLink>; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Starkey+MR%22">Starkey MR</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Dept of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Pillar+AL%22">Pillar AL</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Donovan+C%22">Donovan C</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Pathinayake+PS%22">Pathinayake PS</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Carroll+OR%22">Carroll OR</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Trinder+D%22">Trinder D</searchLink>; Medical School, Harry Perkins Medical Research Institute, University of Western Australia, Fiona Stanley Hospital, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Tay+HL%22">Tay HL</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Badi+YE%22">Badi YE</searchLink>; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kermani+NZ%22">Kermani NZ</searchLink>; Data Science Institute, Dept of Computing, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Guo+YK%22">Guo YK</searchLink>; Data Science Institute, Dept of Computing, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Aryal+R%22">Aryal R</searchLink>; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Mumby+S%22">Mumby S</searchLink>; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pavlidis+S%22">Pavlidis S</searchLink>; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Adcock+IM%22">Adcock IM</searchLink>; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Weaver+J%22">Weaver J</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Xenaki+D%22">Xenaki D</searchLink>; Woolcock Institute of Medical Research, University of Sydney and School of Life Sciences, University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Oliver+BG%22">Oliver BG</searchLink>; Woolcock Institute of Medical Research, University of Sydney and School of Life Sciences, University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Holliday+EG%22">Holliday EG</searchLink>; Hunter Medical Research Institute, New Lambton, Australia.; School of Medicine and Public Health, University of Newcastle, Callaghan, Australia.<br /><searchLink fieldCode="AU" term="%22Foster+PS%22">Foster PS</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Wark+PA%22">Wark PA</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Dept of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Johnstone+DM%22">Johnstone DM</searchLink>; Discipline of Physiology and Bosch Institute, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Milward+EA%22">Milward EA</searchLink>; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Hansbro+PM%22">Hansbro PM</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Horvat+JC%22">Horvat JC</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.; These authors contributed equally.
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  Data: <searchLink fieldCode="JN" term="%228803460%22">The European respiratory journal</searchLink> [Eur Respir J] 2020 Apr 23; Vol. 55 (4). <i>Date of Electronic Publication: </i>2020 Apr 23 (<i>Print Publication: </i>2020).
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