Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation.
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| Title: | Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation. |
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| Authors: | Patsoukis N; Division of Hematology-Oncology Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Duke-Cohan JS; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA., Chaudhri A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA., Aksoylar HI; Division of Hematology-Oncology Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Wang Q; Division of Hematology-Oncology Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Council A; Division of Hematology-Oncology Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Berg A; Department of Pathology Beth Israel Deaconess Cancer Center, Harvard Medical School, Boston, MA, 02215, USA.; Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA., Boussiotis VA; Division of Hematology-Oncology Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. vboussio@bidmc.harvard.edu.; Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA. vboussio@bidmc.harvard.edu. |
| Source: | Communications biology [Commun Biol] 2020 Mar 17; Vol. 3 (1), pp. 128. Date of Electronic Publication: 2020 Mar 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-020-0845-0 |
