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Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.

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Title: Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.
Authors: Chen HY; Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada.; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Cairns BJ; MRC (Medical Research Council) Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Small AM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Burr HA; Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada.; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Ambikkumar A; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Martinsson A; Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden.; Department of Cardiology, Skåne University Hospital, Lund, Sweden., Thériault S; Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada., Munter HM; McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada., Steffen B; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota., Zhang R; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Levinson RT; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, Tennessee., Shaffer CM; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, Tennessee., Rong J; National Heart, Lung, and Blood Institute, Bethesda, Maryland.; Boston University's Framingham Heart Study, Boston, Massachusetts., Sonestedt E; Nutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Dufresne L; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Ljungberg J; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Näslund U; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Johansson B; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Ranatunga DK; Division of Research, Kaiser Permanente of Northern California, Oakland., Whitmer RA; Department of Public Health Sciences, University of California, Davis., Budoff MJ; Los Angeles Biomedical Research Institute, Torrance, California.; Departments of Pediatrics and Medicine at Harbor-UCLA (University of California, Los Angeles) Medical Center, Torrance., Nguyen A; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada., Vasan RS; National Heart, Lung, and Blood Institute, Bethesda, Maryland.; Boston University's Framingham Heart Study, Boston, Massachusetts., Larson MG; National Heart, Lung, and Blood Institute, Bethesda, Maryland.; Boston University's Framingham Heart Study, Boston, Massachusetts., Harris WS; Department of Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota.; OmegaQuant Analytics LLC, Sioux Falls, South Dakota., Damrauer SM; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Stark KD; Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada., Boekholdt SM; Department of Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Pibarot P; Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada., Arsenault BJ; Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada., Mathieu P; Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavík., O'Donnell CJ; National Heart, Lung, and Blood Institute, Bethesda, Maryland.; Boston University's Framingham Heart Study, Boston, Massachusetts., Rotter JI; Los Angeles Biomedical Research Institute, Torrance, California.; Departments of Pediatrics and Medicine at Harbor-UCLA (University of California, Los Angeles) Medical Center, Torrance., Tsai MY; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota., Post WS; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Clarke R; MRC (Medical Research Council) Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Söderberg S; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Bossé Y; Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada., Wells QS; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, Tennessee., Smith JG; Department of Cardiology, Skåne University Hospital, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Lund University Diabetes Center, Lund University, Lund, Sweden., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Lathrop M; McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Engert JC; Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada.; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Thanassoulis G; Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada.; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.
Source: JAMA cardiology [JAMA Cardiol] 2020 Jun 01; Vol. 5 (6), pp. 694-702.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101676033 Publication Model: Print Cited Medium: Internet ISSN: 2380-6591 (Electronic) NLM ISO Abbreviation: JAMA Cardiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.
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Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Ljungberg+J%22">Ljungberg J</searchLink>; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Näslund+U%22">Näslund U</searchLink>; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Johansson+B%22">Johansson B</searchLink>; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Ranatunga+DK%22">Ranatunga DK</searchLink>; Division of Research, Kaiser Permanente of Northern California, Oakland.<br /><searchLink fieldCode="AU" term="%22Whitmer+RA%22">Whitmer RA</searchLink>; Department of Public Health Sciences, University of California, Davis.<br /><searchLink fieldCode="AU" term="%22Budoff+MJ%22">Budoff MJ</searchLink>; Los Angeles Biomedical Research Institute, Torrance, California.; 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