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Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.

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Title: Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.
Authors: Deng X; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA., Chen Y; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA., Mielech AM; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA., Hackbart M; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA., Kesely KR; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA., Mettelman RC; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA., O'Brien A; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA., Chapman ME; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA., Mesecar AD; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA., Baker SC; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA sbaker1@luc.edu.
Source: Journal of virology [J Virol] 2020 May 18; Vol. 94 (11). Date of Electronic Publication: 2020 May 18 (Print Publication: 2020).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.
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  Data: <searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Mielech+AM%22">Mielech AM</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Hackbart+M%22">Hackbart M</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Kesely+KR%22">Kesely KR</searchLink>; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Mettelman+RC%22">Mettelman RC</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22O'Brien+A%22">O'Brien A</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+ME%22">Chapman ME</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Mesecar+AD%22">Mesecar AD</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Baker+SC%22">Baker SC</searchLink>; Department of Microbiology and Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA sbaker1@luc.edu.
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  Data: <searchLink fieldCode="JN" term="%220113724%22">Journal of virology</searchLink> [J Virol] 2020 May 18; Vol. 94 (11). <i>Date of Electronic Publication: </i>2020 May 18 (<i>Print Publication: </i>2020).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+For+Microbiology%22">American Society For Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0113724 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-5514 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220022538X%22">0022538X </searchLink><i>NLM ISO Abbreviation: </i>J Virol <i>Subsets: </i>MEDLINE
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        Value: 10.1128/JVI.01734-19
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              Text: 2020 May 18
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