The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development.

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Title: The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development.
Authors: Demetz E; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Tymoszuk P; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Hilbe R; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Volani C; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Haschka D; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Heim C; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Auer K; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Lener D; Department of Internal Medicine III, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Zeiger LB; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Pfeifhofer-Obermair C; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Boehm A; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Obermair GJ; Department of Physiology and Medical Physics, Medical University of Innsbruck, Fritz-Pregl-Straße 3, 6020 Innsbruck, Austria.; Division of Physiology, Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Straße 30, 3500 Krems, Austria., Ablinger C; Department of Physiology and Medical Physics, Medical University of Innsbruck, Fritz-Pregl-Straße 3, 6020 Innsbruck, Austria., Coassin S; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria., Lamina C; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria., Kager J; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Petzer V; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Asshoff M; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Schroll A; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Nairz M; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Dichtl S; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Seifert M; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria., von Raffay L; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Fischer C; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Barros-Pinkelnig M; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Brigo N; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Valente de Souza L; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria., Sopper S; Department of Internal Medicine V, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Hirsch J; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Graber M; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Gollmann-Tepeköylü C; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Holfeld J; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Halper J; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Macheiner S; Department of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Gostner J; Division of Medical Biochemistry, Medical University of Innsbruck, Innrain 80/IV, 6020 Innsbruck, Austria., Vogel GF; Department of Pediatrics I, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Pechlaner R; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Moser P; Department of Pathology, Innsbruck University Hospital, Anichstraße 35, 6020 Innsbruck, Austria., Imboden M; Swiss Tropical and Public Health Institute, Socinstraße 57, 4051 Basel, Switzerland.; Department of Public Health, University of Basel, Bernoullistraße 28, 4056 Basel, Switzerland., Marques-Vidal P; Department of Internal Medicine, Lausanne University Hospital, Rue du Bugnon 46, 1011 Lausanne, Switzerland., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Socinstraße 57, 4051 Basel, Switzerland.; Department of Public Health, University of Basel, Bernoullistraße 28, 4056 Basel, Switzerland., Meiselbach H; Department of Nephrology and Hypertension, University Hospital Erlangen, Maximiliansplatz 2, 91054 Erlangen, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Marchioninistraße 15, 81377 Munich, Germany., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; German Center for Diabetes Research, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; German Center for Cardiovascular Research, Lazarettstraße 36, 80636 Munich, Germany., Paulweber B; First Department of Medicine, Paracelsus Medical University Salzburg, Strubergasse 21, 5020 Salzburg, Austria., Willeit J; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Kiechl S; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Kronenberg F; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria., Theurl I; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Tancevski I; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria., Weiss G; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria.
Source: European heart journal [Eur Heart J] 2020 Oct 21; Vol. 41 (40), pp. 3949-3959.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development.
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  Data: <searchLink fieldCode="AU" term="%22Demetz+E%22">Demetz E</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Tymoszuk+P%22">Tymoszuk P</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Hilbe+R%22">Hilbe R</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Volani+C%22">Volani C</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Haschka+D%22">Haschka D</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Heim+C%22">Heim C</searchLink>; 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Department of Physiology and Medical Physics, Medical University of Innsbruck, Fritz-Pregl-Straße 3, 6020 Innsbruck, Austria.; Division of Physiology, Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Straße 30, 3500 Krems, Austria.<br /><searchLink fieldCode="AU" term="%22Ablinger+C%22">Ablinger C</searchLink>; Department of Physiology and Medical Physics, Medical University of Innsbruck, Fritz-Pregl-Straße 3, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Coassin+S%22">Coassin S</searchLink>; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Lamina+C%22">Lamina C</searchLink>; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Kager+J%22">Kager J</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Petzer+V%22">Petzer V</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Asshoff+M%22">Asshoff M</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Schroll+A%22">Schroll A</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Nairz+M%22">Nairz M</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Dichtl+S%22">Dichtl S</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Seifert+M%22">Seifert M</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22von+Raffay+L%22">von Raffay L</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Fischer+C%22">Fischer C</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Barros-Pinkelnig+M%22">Barros-Pinkelnig M</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Brigo+N%22">Brigo N</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Valente+de+Souza+L%22">Valente de Souza L</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Sopper+S%22">Sopper S</searchLink>; Department of Internal Medicine V, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Hirsch+J%22">Hirsch J</searchLink>; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Graber+M%22">Graber M</searchLink>; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Gollmann-Tepeköylü+C%22">Gollmann-Tepeköylü C</searchLink>; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Holfeld+J%22">Holfeld J</searchLink>; Department of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Halper+J%22">Halper J</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Macheiner+S%22">Macheiner S</searchLink>; Department of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Gostner+J%22">Gostner J</searchLink>; Division of Medical Biochemistry, Medical University of Innsbruck, Innrain 80/IV, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Vogel+GF%22">Vogel GF</searchLink>; Department of Pediatrics I, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Pechlaner+R%22">Pechlaner R</searchLink>; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Moser+P%22">Moser P</searchLink>; Department of Pathology, Innsbruck University Hospital, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Imboden+M%22">Imboden M</searchLink>; Swiss Tropical and Public Health Institute, Socinstraße 57, 4051 Basel, Switzerland.; Department of Public Health, University of Basel, Bernoullistraße 28, 4056 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marques-Vidal+P%22">Marques-Vidal P</searchLink>; Department of Internal Medicine, Lausanne University Hospital, Rue du Bugnon 46, 1011 Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Probst-Hensch+NM%22">Probst-Hensch NM</searchLink>; Swiss Tropical and Public Health Institute, Socinstraße 57, 4051 Basel, Switzerland.; Department of Public Health, University of Basel, Bernoullistraße 28, 4056 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Meiselbach+H%22">Meiselbach H</searchLink>; Department of Nephrology and Hypertension, University Hospital Erlangen, Maximiliansplatz 2, 91054 Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Strauch+K%22">Strauch K</searchLink>; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Marchioninistraße 15, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+A%22">Peters A</searchLink>; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; German Center for Diabetes Research, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.; German Center for Cardiovascular Research, Lazarettstraße 36, 80636 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Paulweber+B%22">Paulweber B</searchLink>; First Department of Medicine, Paracelsus Medical University Salzburg, Strubergasse 21, 5020 Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Willeit+J%22">Willeit J</searchLink>; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Kiechl+S%22">Kiechl S</searchLink>; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Kronenberg+F%22">Kronenberg F</searchLink>; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Theurl+I%22">Theurl I</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Tancevski+I%22">Tancevski I</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Weiss+G%22">Weiss G</searchLink>; Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Innsbruck, Austria.
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      – PersonEntity:
          Name:
            NameFull: Probst-Hensch NM
      – PersonEntity:
          Name:
            NameFull: Meiselbach H
      – PersonEntity:
          Name:
            NameFull: Strauch K
      – PersonEntity:
          Name:
            NameFull: Peters A
      – PersonEntity:
          Name:
            NameFull: Paulweber B
      – PersonEntity:
          Name:
            NameFull: Willeit J
      – PersonEntity:
          Name:
            NameFull: Kiechl S
      – PersonEntity:
          Name:
            NameFull: Kronenberg F
      – PersonEntity:
          Name:
            NameFull: Theurl I
      – PersonEntity:
          Name:
            NameFull: Tancevski I
      – PersonEntity:
          Name:
            NameFull: Weiss G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 10
              Text: 2020 Oct 21
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 1522-9645
          Numbering:
            – Type: volume
              Value: 41
            – Type: issue
              Value: 40
          Titles:
            – TitleFull: European heart journal
              Type: main
ResultId 1