Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity.

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Title: Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity.
Authors: Nadar RA; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands., Farbod K; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands., der Schilden KC; Nuclear Research & Consultancy Group, Westerduinweg 3, 1755, LE, Petten, The Netherlands., Schlatt L; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany., Crone B; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany., Asokan N; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany., Curci A; Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125, Bari, Italy., Brand M; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany., Bornhaeuser M; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.; National Center for Tumor Diseases (NCT), Fetscherstrasse 74/PF 64, 01307, Dresden, Germany.; German Consortium for Translational Cancer Research (DKTK), DKFZ, D-69120, Heidelberg, Germany., Iafisco M; Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64, 48018, Faenza, Italy., Margiotta N; Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125, Bari, Italy., Karst U; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany., Heskamp S; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands., Boerman OC; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands., van den Beucken JJJP; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands., Leeuwenburgh SCG; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands. sander.leeuwenburgh@radboudumc.nl.; Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64, 48018, Faenza, Italy. sander.leeuwenburgh@radboudumc.nl.
Source: Scientific reports [Sci Rep] 2020 Apr 03; Vol. 10 (1), pp. 5889. Date of Electronic Publication: 2020 Apr 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity.
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  Data: <searchLink fieldCode="AU" term="%22Nadar+RA%22">Nadar RA</searchLink>; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Farbod+K%22">Farbod K</searchLink>; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22der+Schilden+KC%22">der Schilden KC</searchLink>; Nuclear Research & Consultancy Group, Westerduinweg 3, 1755, LE, Petten, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schlatt+L%22">Schlatt L</searchLink>; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Crone+B%22">Crone B</searchLink>; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Asokan+N%22">Asokan N</searchLink>; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Curci+A%22">Curci A</searchLink>; Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Brand+M%22">Brand M</searchLink>; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Bornhaeuser+M%22">Bornhaeuser M</searchLink>; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstrasse 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.; National Center for Tumor Diseases (NCT), Fetscherstrasse 74/PF 64, 01307, Dresden, Germany.; German Consortium for Translational Cancer Research (DKTK), DKFZ, D-69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Iafisco+M%22">Iafisco M</searchLink>; Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64, 48018, Faenza, Italy.<br /><searchLink fieldCode="AU" term="%22Margiotta+N%22">Margiotta N</searchLink>; Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Karst+U%22">Karst U</searchLink>; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Heskamp+S%22">Heskamp S</searchLink>; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boerman+OC%22">Boerman OC</searchLink>; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Beucken+JJJP%22">van den Beucken JJJP</searchLink>; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leeuwenburgh+SCG%22">Leeuwenburgh SCG</searchLink>; Department of Dentistry - Regenerative Biomaterials, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, 6525, EX, Nijmegen, The Netherlands. sander.leeuwenburgh@radboudumc.nl.; Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64, 48018, Faenza, Italy. sander.leeuwenburgh@radboudumc.nl.
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