Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes.

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Title: Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes.
Authors: Tadros HJ; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States; Department of Pediatrics, University of Florida, Gainesville, FL, United States., Life CS; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States., Garcia G; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States., Pirozzi E; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, United States., Jones EG; Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States., Datta S; Department of Biostatistics, University of Florida, Gainesville, FL, United States., Parvatiyar MS; Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, United States., Chase PB; Department of Biological Science, Florida State University, Tallahassee, FL, United States., Allen HD; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States., Kim JJ; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States., Pinto JR; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States., Landstrom AP; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, United States. Electronic address: andrew.landstrom@duke.edu.
Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2020 May; Vol. 142, pp. 118-125. Date of Electronic Publication: 2020 Apr 09.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes.
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  Data: <searchLink fieldCode="AU" term="%22Tadros+HJ%22">Tadros HJ</searchLink>; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States; Department of Pediatrics, University of Florida, Gainesville, FL, United States.<br /><searchLink fieldCode="AU" term="%22Life+CS%22">Life CS</searchLink>; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States.<br /><searchLink fieldCode="AU" term="%22Garcia+G%22">Garcia G</searchLink>; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States.<br /><searchLink fieldCode="AU" term="%22Pirozzi+E%22">Pirozzi E</searchLink>; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Jones+EG%22">Jones EG</searchLink>; Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States.<br /><searchLink fieldCode="AU" term="%22Datta+S%22">Datta S</searchLink>; Department of Biostatistics, University of Florida, Gainesville, FL, United States.<br /><searchLink fieldCode="AU" term="%22Parvatiyar+MS%22">Parvatiyar MS</searchLink>; Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, United States.<br /><searchLink fieldCode="AU" term="%22Chase+PB%22">Chase PB</searchLink>; Department of Biological Science, Florida State University, Tallahassee, FL, United States.<br /><searchLink fieldCode="AU" term="%22Allen+HD%22">Allen HD</searchLink>; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States.<br /><searchLink fieldCode="AU" term="%22Kim+JJ%22">Kim JJ</searchLink>; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States.<br /><searchLink fieldCode="AU" term="%22Pinto+JR%22">Pinto JR</searchLink>; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, United States.<br /><searchLink fieldCode="AU" term="%22Landstrom+AP%22">Landstrom AP</searchLink>; Department of Pediatrics, Section of Cardiology, Baylor College of Medicine, Houston, TX, United States; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, United States. Electronic address: andrew.landstrom@duke.edu.
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  Data: <searchLink fieldCode="JN" term="%220262322%22">Journal of molecular and cellular cardiology</searchLink> [J Mol Cell Cardiol] 2020 May; Vol. 142, pp. 118-125. <i>Date of Electronic Publication: </i>2020 Apr 09.
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