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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

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Title: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
Authors: Emdin CA; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Haas ME; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Khera AV; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Aragam K; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Chaffin M; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Klarin D; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Hindy G; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Jiang L; Departments of Biomedical Informatics, Vanderbilt University, Vanderbilt, Tennessee, United States of America.; Departments of Medicine, Vanderbilt University, Vanderbilt, Tennessee, United States of America., Wei WQ; Departments of Biomedical Informatics, Vanderbilt University, Vanderbilt, Tennessee, United States of America., Feng Q; Departments of Medicine, Vanderbilt University, Vanderbilt, Tennessee, United States of America., Karjalainen J; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, FI, Helsinki, Finland., Havulinna A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, FI, Helsinki, Finland., Kiiskinen T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, FI, Helsinki, Finland., Bick A; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Ardissino D; Division of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.; Associazione per lo Studio Della Trombosi in Cardiologia, Pavia, Italy., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Schunkert H; Deutsches Herzzentrum München, Technische Universität München, Deutsches Zentrum für Herz-Kreislauf-Forschung, München, Germany., McPherson R; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Elosua R; Cardiovascular Epidemiology and Genetics, Hospital del Mar Research Institute, Barcelona, Spain.; CIBER Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain.; Facultat de Medicina, Universitat de Vic-Central de Cataluña, Vic, Spain., Bown MJ; Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Biomedical Research Centre, Leicester, United Kingdom., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Biomedical Research Centre, Leicester, United Kingdom., Baber U; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Erdmann J; Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck, Germany., Gupta N; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Danesh J; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.; National Institute of Health Research Blood and Transplant; Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom., Saleheen D; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Center for Non-Communicable Diseases, Karachi, Pakistan., Chang KM; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Vujkovic M; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Voight B; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Damrauer S; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Lynch J; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Kaplan D; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Serper M; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Tsao P; Veterans Affairs Palo Alto Health Care System, Palo Alto, California, United States of America., Mercader J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Hanis C; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Daly M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, FI, Helsinki, Finland., Denny J; Departments of Biomedical Informatics, Vanderbilt University, Vanderbilt, Tennessee, United States of America.; Departments of Medicine, Vanderbilt University, Vanderbilt, Tennessee, United States of America., Gabriel S; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Kathiresan S; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Verve Therapeutics, Boston, Massachusetts, United States of America.
Corporate Authors: Million Veteran Program
Source: PLoS genetics [PLoS Genet] 2020 Apr 13; Vol. 16 (4), pp. e1008629. Date of Electronic Publication: 2020 Apr 13 (Print Publication: 2020).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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