Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity.

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Title: Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity.
Authors: Jestin M; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Kapnick SM; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Tarasenko TN; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Burke CT; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Zerfas PM; Office of Research Services, National Institutes of Health, Bethesda, MD, 20892, USA., Diaz F; University of Miami, Department of Neurology, Miller School of Medicine, Miami, FL, 33136, USA., Vernon H; Kennedy Krieger Institute, Johns Hopkins Medical Center, Baltimore, MD, 21205, USA., Singh LN; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Sokol RJ; Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO 80045, USA., McGuire PJ; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. Electronic address: peter.mcguire@nih.gov.
Source: Molecular metabolism [Mol Metab] 2020 Jul; Vol. 37, pp. 100981. Date of Electronic Publication: 2020 Mar 26.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity.
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  Data: <searchLink fieldCode="AU" term="%22Jestin+M%22">Jestin M</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Kapnick+SM%22">Kapnick SM</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Tarasenko+TN%22">Tarasenko TN</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Burke+CT%22">Burke CT</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Zerfas+PM%22">Zerfas PM</searchLink>; Office of Research Services, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Diaz+F%22">Diaz F</searchLink>; University of Miami, Department of Neurology, Miller School of Medicine, Miami, FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Vernon+H%22">Vernon H</searchLink>; Kennedy Krieger Institute, Johns Hopkins Medical Center, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Singh+LN%22">Singh LN</searchLink>; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Sokol+RJ%22">Sokol RJ</searchLink>; Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22McGuire+PJ%22">McGuire PJ</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. Electronic address: peter.mcguire@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101605730%22">Molecular metabolism</searchLink> [Mol Metab] 2020 Jul; Vol. 37, pp. 100981. <i>Date of Electronic Publication: </i>2020 Mar 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+GmbH%22">Elsevier GmbH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101605730 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2212-8778 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222128778%22">22128778 </searchLink><i>NLM ISO Abbreviation: </i>Mol Metab <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.molmet.2020.100981
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        Text: English
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              Text: 2020 Jul
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