An Alzheimer Disease Challenge Model: 24-Hour Sleep Deprivation in Healthy Volunteers, Impact on Working Memory, and Reversal Effect of Pharmacological Intervention: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

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Title: An Alzheimer Disease Challenge Model: 24-Hour Sleep Deprivation in Healthy Volunteers, Impact on Working Memory, and Reversal Effect of Pharmacological Intervention: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Authors: Chan Kwong A; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Cassé-Perrot C; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Costes-Salon MC; MEDES-Institut de Médecine et de Physiologie Spatiale; Clinique Spatiale, Toulouse., Jouve E; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Lanteaume L; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Audebert C; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Rouby F; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Lefebvre MN; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Ranjeva JP; Aix Marseille Université, CNRS, CRMBM 7339, Marseille., Beck A; MEDES-Institut de Médecine et de Physiologie Spatiale; Clinique Spatiale, Toulouse., Deplanque D; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille., Ponchel A; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille., Vervueren C; INSERM, Imagerie Cérébrale et Handicaps Neurologiques UMR 825, Toulouse, France., Truillet R; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Babilon C; Department of Physiology and Pharmacology, University of Rome 'La Sapienza,' Rome, Italy., Auffret A; ICM, Institut du Cerveau et de la Moelle épinière, Hôpital Pitié Salpêtrière, Paris, France., Richardson JC; Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Stevenage, United Kingdom., Payoux P; INSERM, Imagerie Cérébrale et Handicaps Neurologiques UMR 825, Toulouse, France., Bartrés-Faz D; Department of Psychiatry and Clinical Psychobiology, Faculty of Medicine, University of Barcelona and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain., Blin O; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille., Bordet R; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille., Micallef J; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.
Corporate Authors: Pharmacog Consortium
Source: Journal of clinical psychopharmacology [J Clin Psychopharmacol] 2020 May/Jun; Vol. 40 (3), pp. 222-230.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Williams And Wilkins Country of Publication: United States NLM ID: 8109496 Publication Model: Print Cited Medium: Internet ISSN: 1533-712X (Electronic) Linking ISSN: 02710749 NLM ISO Abbreviation: J Clin Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An Alzheimer Disease Challenge Model: 24-Hour Sleep Deprivation in Healthy Volunteers, Impact on Working Memory, and Reversal Effect of Pharmacological Intervention: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
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  Data: <searchLink fieldCode="AU" term="%22Chan+Kwong+A%22">Chan Kwong A</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Cassé-Perrot+C%22">Cassé-Perrot C</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Costes-Salon+MC%22">Costes-Salon MC</searchLink>; MEDES-Institut de Médecine et de Physiologie Spatiale; Clinique Spatiale, Toulouse.<br /><searchLink fieldCode="AU" term="%22Jouve+E%22">Jouve E</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Lanteaume+L%22">Lanteaume L</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Audebert+C%22">Audebert C</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Rouby+F%22">Rouby F</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Lefebvre+MN%22">Lefebvre MN</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Ranjeva+JP%22">Ranjeva JP</searchLink>; Aix Marseille Université, CNRS, CRMBM 7339, Marseille.<br /><searchLink fieldCode="AU" term="%22Beck+A%22">Beck A</searchLink>; MEDES-Institut de Médecine et de Physiologie Spatiale; Clinique Spatiale, Toulouse.<br /><searchLink fieldCode="AU" term="%22Deplanque+D%22">Deplanque D</searchLink>; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille.<br /><searchLink fieldCode="AU" term="%22Ponchel+A%22">Ponchel A</searchLink>; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille.<br /><searchLink fieldCode="AU" term="%22Vervueren+C%22">Vervueren C</searchLink>; INSERM, Imagerie Cérébrale et Handicaps Neurologiques UMR 825, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Truillet+R%22">Truillet R</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Babilon+C%22">Babilon C</searchLink>; Department of Physiology and Pharmacology, University of Rome 'La Sapienza,' Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Auffret+A%22">Auffret A</searchLink>; ICM, Institut du Cerveau et de la Moelle épinière, Hôpital Pitié Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Richardson+JC%22">Richardson JC</searchLink>; Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Payoux+P%22">Payoux P</searchLink>; INSERM, Imagerie Cérébrale et Handicaps Neurologiques UMR 825, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bartrés-Faz+D%22">Bartrés-Faz D</searchLink>; Department of Psychiatry and Clinical Psychobiology, Faculty of Medicine, University of Barcelona and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain.<br /><searchLink fieldCode="AU" term="%22Blin+O%22">Blin O</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.<br /><searchLink fieldCode="AU" term="%22Bordet+R%22">Bordet R</searchLink>; University of Lille, Inserm, CHU Lille, U1171-Degenerative and Vascular Cognitive Disorders, Lille.<br /><searchLink fieldCode="AU" term="%22Micallef+J%22">Micallef J</searchLink>; From the Aix Marseille Université, APHM, INSERM, CIC CPCET Service de Pharmacologie Clinique et Pharmacovigilance, Institut de Neurosciences des Systèmes, Marseille.
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