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DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies.

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Title: DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies.
Authors: Oostindie SC; Genmab, Utrecht, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., van der Horst HJ; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Kil LP; Genmab, Utrecht, The Netherlands., Strumane K; Genmab, Utrecht, The Netherlands., Overdijk MB; Genmab, Utrecht, The Netherlands., van den Brink EN; Genmab, Utrecht, The Netherlands., van den Brakel JHN; Genmab, Utrecht, The Netherlands., Rademaker HJ; Genmab, Utrecht, The Netherlands., van Kessel B; Genmab, Utrecht, The Netherlands., van den Noort J; Genmab, Utrecht, The Netherlands., Chamuleau MED; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Mutis T; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Lindorfer MA; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA., Taylor RP; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA., Schuurman J; Genmab, Utrecht, The Netherlands., Parren PWHI; Genmab, Utrecht, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.; Lava Therapeutics, Utrecht, The Netherlands., Beurskens FJ; Genmab, Utrecht, The Netherlands., Breij ECW; Genmab, Utrecht, The Netherlands. ebj@genmab.com.
Source: Blood cancer journal [Blood Cancer J] 2020 Apr 28; Vol. 10 (3), pp. 30. Date of Electronic Publication: 2020 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DuoHexaBody-CD37<superscript>®</superscript>, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies.
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  Data: <searchLink fieldCode="AU" term="%22Oostindie+SC%22">Oostindie SC</searchLink>; Genmab, Utrecht, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Horst+HJ%22">van der Horst HJ</searchLink>; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kil+LP%22">Kil LP</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Strumane+K%22">Strumane K</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Overdijk+MB%22">Overdijk MB</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Brink+EN%22">van den Brink EN</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Brakel+JHN%22">van den Brakel JHN</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rademaker+HJ%22">Rademaker HJ</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Kessel+B%22">van Kessel B</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Noort+J%22">van den Noort J</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Chamuleau+MED%22">Chamuleau MED</searchLink>; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mutis+T%22">Mutis T</searchLink>; Department of Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lindorfer+MA%22">Lindorfer MA</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+RP%22">Taylor RP</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Schuurman+J%22">Schuurman J</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Parren+PWHI%22">Parren PWHI</searchLink>; Genmab, Utrecht, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.; Lava Therapeutics, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Beurskens+FJ%22">Beurskens FJ</searchLink>; Genmab, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Breij+ECW%22">Breij ECW</searchLink>; Genmab, Utrecht, The Netherlands. ebj@genmab.com.
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  Data: <searchLink fieldCode="JN" term="%22101568469%22">Blood cancer journal</searchLink> [Blood Cancer J] 2020 Apr 28; Vol. 10 (3), pp. 30. <i>Date of Electronic Publication: </i>2020 Apr 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101568469 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2044-5385 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220445385%22">20445385 </searchLink><i>NLM ISO Abbreviation: </i>Blood Cancer J <i>Subsets: </i>MEDLINE
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