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Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis.

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Title: Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis.
Authors: Vanneste M; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States., Feddersen CR; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Varzavand A; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA, United States., Zhu EY; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Foley T; Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Zhao L; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States., Holt KH; Viral Vector Core Facility, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Milhem M; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Piper R; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Stipp CS; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Dupuy AJ; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Henry MD; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States.; Department of Radiation Oncology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Department of Urology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.
Source: Frontiers in oncology [Front Oncol] 2020 Apr 03; Vol. 10, pp. 442. Date of Electronic Publication: 2020 Apr 03 (Print Publication: 2020).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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