View in EDS HTML Full Text PDF Full Text

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.

Saved in:
Bibliographic Details
Title: Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
Authors: Post KL; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Belmadani M; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada., Ganguly P; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Meili F; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Dingwall R; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., McDiarmid TA; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Psychology, University of British Columbia, Vancouver, Canada., Meyers WM; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Herrington C; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Young BP; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Callaghan DB; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada., Rogic S; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada., Edwards M; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Niciforovic A; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Cau A; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Rankin CH; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Psychology, University of British Columbia, Vancouver, Canada., O'Connor TP; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Bamji SX; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Loewen CJR; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Allan DW; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada., Pavlidis P; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca.; Department of Psychiatry, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca., Haas K; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada. kurt.haas@ubc.ca.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada. kurt.haas@ubc.ca.
Source: Nature communications [Nat Commun] 2020 Apr 29; Vol. 11 (1), pp. 2073. Date of Electronic Publication: 2020 Apr 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 32350270
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Post+KL%22">Post KL</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Belmadani+M%22">Belmadani M</searchLink>; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Ganguly+P%22">Ganguly P</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Meili+F%22">Meili F</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Dingwall+R%22">Dingwall R</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22McDiarmid+TA%22">McDiarmid TA</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Psychology, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Meyers+WM%22">Meyers WM</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Herrington+C%22">Herrington C</searchLink>; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Young+BP%22">Young BP</searchLink>; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Callaghan+DB%22">Callaghan DB</searchLink>; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Rogic+S%22">Rogic S</searchLink>; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Edwards+M%22">Edwards M</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Niciforovic+A%22">Niciforovic A</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Cau+A%22">Cau A</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Rankin+CH%22">Rankin CH</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Psychology, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22O'Connor+TP%22">O'Connor TP</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Bamji+SX%22">Bamji SX</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Loewen+CJR%22">Loewen CJR</searchLink>; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Allan+DW%22">Allan DW</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Pavlidis+P%22">Pavlidis P</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca.; Department of Psychiatry, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca.; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada. paul@msl.ubc.ca.<br /><searchLink fieldCode="AU" term="%22Haas+K%22">Haas K</searchLink>; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada. kurt.haas@ubc.ca.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada. kurt.haas@ubc.ca.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2020 Apr 29; Vol. 11 (1), pp. 2073. <i>Date of Electronic Publication: </i>2020 Apr 29.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32350270
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-020-15943-0
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2073
    Titles:
      – TitleFull: Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Post KL
      – PersonEntity:
          Name:
            NameFull: Belmadani M
      – PersonEntity:
          Name:
            NameFull: Ganguly P
      – PersonEntity:
          Name:
            NameFull: Meili F
      – PersonEntity:
          Name:
            NameFull: Dingwall R
      – PersonEntity:
          Name:
            NameFull: McDiarmid TA
      – PersonEntity:
          Name:
            NameFull: Meyers WM
      – PersonEntity:
          Name:
            NameFull: Herrington C
      – PersonEntity:
          Name:
            NameFull: Young BP
      – PersonEntity:
          Name:
            NameFull: Callaghan DB
      – PersonEntity:
          Name:
            NameFull: Rogic S
      – PersonEntity:
          Name:
            NameFull: Edwards M
      – PersonEntity:
          Name:
            NameFull: Niciforovic A
      – PersonEntity:
          Name:
            NameFull: Cau A
      – PersonEntity:
          Name:
            NameFull: Rankin CH
      – PersonEntity:
          Name:
            NameFull: O'Connor TP
      – PersonEntity:
          Name:
            NameFull: Bamji SX
      – PersonEntity:
          Name:
            NameFull: Loewen CJR
      – PersonEntity:
          Name:
            NameFull: Allan DW
      – PersonEntity:
          Name:
            NameFull: Pavlidis P
      – PersonEntity:
          Name:
            NameFull: Haas K
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 29
              M: 04
              Text: 2020 Apr 29
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 11
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1