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Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology.

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Title: Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology.
Authors: Rovida C; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany., Barton-Maclaren T; Existing Substances Risk Assessment Bureau, Health Canada, Ottawa, Canada., Benfenati E; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Caloni F; Università degli Studi di Milano, Department of Veterinary Medicine (DIMEVET) Milan, Italy., Chandrasekera PC; Canadian Centre for Alternatives to Animal Methods, University of Windsor, Ontario, Canada, Chesné C; Biopredic International, Saint Grégoire, France., Cronin MTD; Liverpool John Moores University, School of Pharmacy and Biomolecular Sciences, Liverpool, UK., De Knecht J; Centre for Safety of Substances and Products, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Dietrich DR; Human and Environmental Toxicology, University of Konstanz, Konstanz, Germany., Escher SE; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., Fitzpatrick S; US Food and Drug Administration, Center for Food Safety and Applied Nutrition, MD, USA., Flannery B; US Food and Drug Administration, Center for Food Safety and Applied Nutrition, MD, USA., Herzler M; German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Hougaard Bennekou S; Danish Environmental Protection Agency, Copenhagen, Denmark / Danish Technical University, FOOD, Lyngby, Denmark., Hubesch B; European Chemical Industry Council (Cefic), Brussels, Belgium., Kamp H; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany., Kisitu J; In vitro Toxicology and Biomedicine, Dept inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Konstanz, Germany., Kleinstreuer N; NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States., Kovarich S; S-IN Soluzioni Informatiche S.r.l., Vicenza, Italy., Leist M; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.; In vitro Toxicology and Biomedicine, Dept inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Konstanz, Germany., Maertens A; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA., Nugent K; Australian Government Department of Health, Canberra, Australia., Pallocca G; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany., Pastor M; Research Programme on Biomedical Informatics (GRIB), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Dept. of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Patlewicz G; Center for Computational Toxicology & Exposure (CCTE), U.S. Environmental Protection Agency, Research Triangle Park, NC, USA., Pavan M; Innovatune S.r.l., Padova, Italy., Presgrave O; Departamento de Farmacologia e Toxicologia, Instituto Nacional de Controle da Qualidade em Saúde, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil., Smirnova L; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA., Schwarz M; University of Tübingen, Tübingen, Germany., Yamada T; National Institute of Health Sciences, Kanagawa, Japan., Hartung T; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA.
Source: ALTEX [ALTEX] 2020; Vol. 37 (4), pp. 579-606. Date of Electronic Publication: 2020 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Spektrum Akademischer Verlag Country of Publication: Germany NLM ID: 100953980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1868-8551 (Electronic) Linking ISSN: 1868596X NLM ISO Abbreviation: ALTEX Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Rovida+C%22">Rovida C</searchLink>; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Barton-Maclaren+T%22">Barton-Maclaren T</searchLink>; Existing Substances Risk Assessment Bureau, Health Canada, Ottawa, Canada.<br /><searchLink fieldCode="AU" term="%22Benfenati+E%22">Benfenati E</searchLink>; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Caloni+F%22">Caloni F</searchLink>; Università degli Studi di Milano, Department of Veterinary Medicine (DIMEVET) Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chandrasekera+PC%22">Chandrasekera PC</searchLink>; Canadian Centre for Alternatives to Animal Methods, University of Windsor, Ontario, Canada<br /><searchLink fieldCode="AU" term="%22Chesné+C%22">Chesné C</searchLink>; Biopredic International, Saint Grégoire, France.<br /><searchLink fieldCode="AU" term="%22Cronin+MTD%22">Cronin MTD</searchLink>; Liverpool John Moores University, School of Pharmacy and Biomolecular Sciences, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22De+Knecht+J%22">De Knecht J</searchLink>; Centre for Safety of Substances and Products, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dietrich+DR%22">Dietrich DR</searchLink>; Human and Environmental Toxicology, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Escher+SE%22">Escher SE</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+S%22">Fitzpatrick S</searchLink>; US Food and Drug Administration, Center for Food Safety and Applied Nutrition, MD, USA.<br /><searchLink fieldCode="AU" term="%22Flannery+B%22">Flannery B</searchLink>; US Food and Drug Administration, Center for Food Safety and Applied Nutrition, MD, USA.<br /><searchLink fieldCode="AU" term="%22Herzler+M%22">Herzler M</searchLink>; German Federal Institute for Risk Assessment (BfR), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hougaard+Bennekou+S%22">Hougaard Bennekou S</searchLink>; Danish Environmental Protection Agency, Copenhagen, Denmark / Danish Technical University, FOOD, Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Hubesch+B%22">Hubesch B</searchLink>; European Chemical Industry Council (Cefic), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Kamp+H%22">Kamp H</searchLink>; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Kisitu+J%22">Kisitu J</searchLink>; In vitro Toxicology and Biomedicine, Dept inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Kleinstreuer+N%22">Kleinstreuer N</searchLink>; NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Kovarich+S%22">Kovarich S</searchLink>; S-IN Soluzioni Informatiche S.r.l., Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Leist+M%22">Leist M</searchLink>; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.; In vitro Toxicology and Biomedicine, Dept inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Maertens+A%22">Maertens A</searchLink>; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nugent+K%22">Nugent K</searchLink>; Australian Government Department of Health, Canberra, Australia.<br /><searchLink fieldCode="AU" term="%22Pallocca+G%22">Pallocca G</searchLink>; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Pastor+M%22">Pastor M</searchLink>; Research Programme on Biomedical Informatics (GRIB), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Dept. of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Patlewicz+G%22">Patlewicz G</searchLink>; Center for Computational Toxicology & Exposure (CCTE), U.S. Environmental Protection Agency, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Pavan+M%22">Pavan M</searchLink>; Innovatune S.r.l., Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Presgrave+O%22">Presgrave O</searchLink>; Departamento de Farmacologia e Toxicologia, Instituto Nacional de Controle da Qualidade em Saúde, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Smirnova+L%22">Smirnova L</searchLink>; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Schwarz+M%22">Schwarz M</searchLink>; University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Yamada+T%22">Yamada T</searchLink>; National Institute of Health Sciences, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hartung+T%22">Hartung T</searchLink>; Center for Alternatives to Animal Testing, CAAT-Europe, University of Konstanz, Konstanz, Germany.; Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, MD, USA.
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