Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
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| Title: | Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes. |
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| Authors: | Saleem U; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., van Meer BJ; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., Katili PA; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK., Mohd Yusof NAN; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK., Mannhardt I; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Garcia AK; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., Tertoolen L; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., de Korte T; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Ncardia, 2333 BD, Leiden, The Netherlands., Vlaming MLH; Ncardia, 2333 BD, Leiden, The Netherlands., McGlynn K; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK., Nebel J; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Bahinski A; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Harris K; NC3Rs, London NW1 2BE, UK., Rossman E; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Xu X; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Burton FL; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Smith GL; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Clements P; GlaxoSmithKline, David Jack Centre for R&D, Ware, Hertfordshire SG12 0DP, UK., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Department Applied Stem Cell Technologies, University of Twente, 7500 EA Enschede, The Netherlands., Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Hansen A; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Denning C; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK. |
| Source: | Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 Jul 01; Vol. 176 (1), pp. 103-123. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1096-0929 |
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| DOI: | 10.1093/toxsci/kfaa058 |
