View in EDS HTML Full Text PDF Full Text

Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.

Saved in:
Bibliographic Details
Title: Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
Authors: Saleem U; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., van Meer BJ; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., Katili PA; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK., Mohd Yusof NAN; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK., Mannhardt I; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Garcia AK; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., Tertoolen L; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands., de Korte T; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Ncardia, 2333 BD, Leiden, The Netherlands., Vlaming MLH; Ncardia, 2333 BD, Leiden, The Netherlands., McGlynn K; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK., Nebel J; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Bahinski A; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Harris K; NC3Rs, London NW1 2BE, UK., Rossman E; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Xu X; GlaxoSmithKline, Collegeville, Pennsylvania 19426., Burton FL; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Smith GL; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Clements P; GlaxoSmithKline, David Jack Centre for R&D, Ware, Hertfordshire SG12 0DP, UK., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Department Applied Stem Cell Technologies, University of Twente, 7500 EA Enschede, The Netherlands., Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Hansen A; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany., Denning C; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 Jul 01; Vol. 176 (1), pp. 103-123.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 32421822
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Saleem+U%22">Saleem U</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22van+Meer+BJ%22">van Meer BJ</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Katili+PA%22">Katili PA</searchLink>; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.<br /><searchLink fieldCode="AU" term="%22Mohd+Yusof+NAN%22">Mohd Yusof NAN</searchLink>; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.<br /><searchLink fieldCode="AU" term="%22Mannhardt+I%22">Mannhardt I</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Garcia+AK%22">Garcia AK</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tertoolen+L%22">Tertoolen L</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Korte+T%22">de Korte T</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Ncardia, 2333 BD, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vlaming+MLH%22">Vlaming MLH</searchLink>; Ncardia, 2333 BD, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22McGlynn+K%22">McGlynn K</searchLink>; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.<br /><searchLink fieldCode="AU" term="%22Nebel+J%22">Nebel J</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Bahinski+A%22">Bahinski A</searchLink>; GlaxoSmithKline, Collegeville, Pennsylvania 19426.<br /><searchLink fieldCode="AU" term="%22Harris+K%22">Harris K</searchLink>; NC3Rs, London NW1 2BE, UK.<br /><searchLink fieldCode="AU" term="%22Rossman+E%22">Rossman E</searchLink>; GlaxoSmithKline, Collegeville, Pennsylvania 19426.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; GlaxoSmithKline, Collegeville, Pennsylvania 19426.<br /><searchLink fieldCode="AU" term="%22Burton+FL%22">Burton FL</searchLink>; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK.<br /><searchLink fieldCode="AU" term="%22Smith+GL%22">Smith GL</searchLink>; Clyde Biosciences Ltd, Biocity Scotland, Newhouse, Lanarkshire ML1 5HU, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK.<br /><searchLink fieldCode="AU" term="%22Clements+P%22">Clements P</searchLink>; GlaxoSmithKline, David Jack Centre for R&D, Ware, Hertfordshire SG12 0DP, UK.<br /><searchLink fieldCode="AU" term="%22Mummery+CL%22">Mummery CL</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD, Leiden, The Netherlands.; Department Applied Stem Cell Technologies, University of Twente, 7500 EA Enschede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Eschenhagen+T%22">Eschenhagen T</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Hansen+A%22">Hansen A</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, and DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Denning+C%22">Denning C</searchLink>; Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229805461%22">Toxicological sciences : an official journal of the Society of Toxicology</searchLink> [Toxicol Sci] 2020 Jul 01; Vol. 176 (1), pp. 103-123.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9805461 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0929 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210960929%22">10960929 </searchLink><i>NLM ISO Abbreviation: </i>Toxicol Sci <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32421822
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1093/toxsci/kfaa058
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 103
    Titles:
      – TitleFull: Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Saleem U
      – PersonEntity:
          Name:
            NameFull: van Meer BJ
      – PersonEntity:
          Name:
            NameFull: Katili PA
      – PersonEntity:
          Name:
            NameFull: Mohd Yusof NAN
      – PersonEntity:
          Name:
            NameFull: Mannhardt I
      – PersonEntity:
          Name:
            NameFull: Garcia AK
      – PersonEntity:
          Name:
            NameFull: Tertoolen L
      – PersonEntity:
          Name:
            NameFull: de Korte T
      – PersonEntity:
          Name:
            NameFull: Vlaming MLH
      – PersonEntity:
          Name:
            NameFull: McGlynn K
      – PersonEntity:
          Name:
            NameFull: Nebel J
      – PersonEntity:
          Name:
            NameFull: Bahinski A
      – PersonEntity:
          Name:
            NameFull: Harris K
      – PersonEntity:
          Name:
            NameFull: Rossman E
      – PersonEntity:
          Name:
            NameFull: Xu X
      – PersonEntity:
          Name:
            NameFull: Burton FL
      – PersonEntity:
          Name:
            NameFull: Smith GL
      – PersonEntity:
          Name:
            NameFull: Clements P
      – PersonEntity:
          Name:
            NameFull: Mummery CL
      – PersonEntity:
          Name:
            NameFull: Eschenhagen T
      – PersonEntity:
          Name:
            NameFull: Hansen A
      – PersonEntity:
          Name:
            NameFull: Denning C
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2020 Jul 01
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 1096-0929
          Numbering:
            – Type: volume
              Value: 176
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Toxicological sciences : an official journal of the Society of Toxicology
              Type: main
ResultId 1