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Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.

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Title: Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.
Authors: Ullman JC; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Arguello A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Getz JA; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Bhalla A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Mahon CS; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Wang J; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Giese T; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Bedard C; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Kim DJ; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Blumenfeld JR; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Liang N; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Ravi R; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Nugent AA; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Davis SS; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Ha C; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Duque J; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Tran HL; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Wells RC; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Lianoglou S; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Daryani VM; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Kwan W; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Solanoy H; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Nguyen H; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Earr T; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Dugas JC; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Tuck MD; Mass Spectrometry Research Center, Vanderbilt University, 9160 MRB III, 465 21 Avenue South, Nashville, TN 37240, USA., Harvey JL; Mass Spectrometry Research Center, Vanderbilt University, 9160 MRB III, 465 21 Avenue South, Nashville, TN 37240, USA., Reyzer ML; Mass Spectrometry Research Center, Vanderbilt University, 9160 MRB III, 465 21 Avenue South, Nashville, TN 37240, USA., Caprioli RM; Mass Spectrometry Research Center, Vanderbilt University, 9160 MRB III, 465 21 Avenue South, Nashville, TN 37240, USA., Hall S; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Poda S; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Sanchez PE; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Dennis MS; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Gunasekaran K; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Srivastava A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Sandmann T; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Henne KR; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Thorne RG; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Di Paolo G; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Astarita G; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Diaz D; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Silverman AP; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Watts RJ; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Sweeney ZK; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA., Kariolis MS; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA. kariolis@dnli.com henry@dnli.com., Henry AG; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, CA 94080, USA. kariolis@dnli.com henry@dnli.com.
Source: Science translational medicine [Sci Transl Med] 2020 May 27; Vol. 12 (545).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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