Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
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| Title: | Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells. |
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| Authors: | Hong SW; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Shin JS; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Moon JH; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Jung SA; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Koh DI; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Ryu Y; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Park YS; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Kim DY; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Park SS; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Hong JK; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Kim EH; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Kim MJ; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Jeong HR; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea., Bae IH; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea., Ahn YG; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea., Suh KH; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea., Cho IJ; Osong Medical Innovation Foundation, Cheongju-si, Republic of Korea., Kang JS; Bioevaluation Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Chungbuk, Republic of Korea., Hong YS; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea., Lee JS; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea., Jin DH; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Department of Medical Sicence, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. inno183@amc.seoul.kr., Kim TW; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea. twkimmd@amc.seoul.kr.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea. twkimmd@amc.seoul.kr. |
| Source: | Investigational new drugs [Invest New Drugs] 2020 Dec; Vol. 38 (6), pp. 1696-1706. Date of Electronic Publication: 2020 May 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32462369 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hong+SW%22">Hong SW</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JS%22">Shin JS</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JH%22">Moon JH</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SA%22">Jung SA</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koh+DI%22">Koh DI</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+Y%22">Ryu Y</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+YS%22">Park YS</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DY%22">Kim DY</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SS%22">Park SS</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+JK%22">Hong JK</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+EH%22">Kim EH</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MJ%22">Kim MJ</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+HR%22">Jeong HR</searchLink>; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+IH%22">Bae IH</searchLink>; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+YG%22">Ahn YG</searchLink>; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Suh+KH%22">Suh KH</searchLink>; Hanmi Research Center, Hanmi Pharm. Co., Ltd, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+IJ%22">Cho IJ</searchLink>; Osong Medical Innovation Foundation, Cheongju-si, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+JS%22">Kang JS</searchLink>; Bioevaluation Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Chungbuk, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+YS%22">Hong YS</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+DH%22">Jin DH</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Department of Medical Science, Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. inno183@amc.seoul.kr.; Department of Medical Sicence, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. inno183@amc.seoul.kr.<br /><searchLink fieldCode="AU" term="%22Kim+TW%22">Kim TW</searchLink>; Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea. twkimmd@amc.seoul.kr.; Department of Oncology, Asan Medical Center, Seoul, Republic of Korea. twkimmd@amc.seoul.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228309330%22">Investigational new drugs</searchLink> [Invest New Drugs] 2020 Dec; Vol. 38 (6), pp. 1696-1706. <i>Date of Electronic Publication: </i>2020 May 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309330 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-0646 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676997%22">01676997 </searchLink><i>NLM ISO Abbreviation: </i>Invest New Drugs <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32462369 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10637-020-00956-9 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1696 Titles: – TitleFull: Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hong SW – PersonEntity: Name: NameFull: Shin JS – PersonEntity: Name: NameFull: Moon JH – PersonEntity: Name: NameFull: Jung SA – PersonEntity: Name: NameFull: Koh DI – PersonEntity: Name: NameFull: Ryu Y – PersonEntity: Name: NameFull: Park YS – PersonEntity: Name: NameFull: Kim DY – PersonEntity: Name: NameFull: Park SS – PersonEntity: Name: NameFull: Hong JK – PersonEntity: Name: NameFull: Kim EH – PersonEntity: Name: NameFull: Kim MJ – PersonEntity: Name: NameFull: Jeong HR – PersonEntity: Name: NameFull: Bae IH – PersonEntity: Name: NameFull: Ahn YG – PersonEntity: Name: NameFull: Suh KH – PersonEntity: Name: NameFull: Cho IJ – PersonEntity: Name: NameFull: Kang JS – PersonEntity: Name: NameFull: Hong YS – PersonEntity: Name: NameFull: Lee JS – PersonEntity: Name: NameFull: Jin DH – PersonEntity: Name: NameFull: Kim TW IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2020 Dec Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1573-0646 Numbering: – Type: volume Value: 38 – Type: issue Value: 6 Titles: – TitleFull: Investigational new drugs Type: main |
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