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Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.

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Title: Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Authors: Verma SS; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bergmeijer TO; Department of Cardiology, St. Antonius Center for Platelet Function Research, Nieuwegein, The Netherlands., Gong L; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Reny JL; Internal Medicine, Béziers Hospital, Béziers, France.; Geneva Platelet Group, School of Medicine, University of Geneva, Geneva, Switzerland.; Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva, Switzerland.; Geneva Platelet Group and Division of Angiology and Haemostasis, University Hospitals of Geneva, Geneva, Switzerland., Lewis JP; Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA., Mitchell BD; Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, USA., Alexopoulos D; National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece., Aradi D; Department of Cardiology, Heart Center Balatonfüred, Balatonfüred, Hungary., Altman RB; Department of Bioengineering, Genetics and Medicine, Stanford University, Stanford, California, USA., Bliden K; Sinai Center for Thrombosis Research and Drug Development, Baltimore, Maryland, USA., Bradford Y; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Campo G; Cardiology Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara and Maria Cecilia Hospital, GVM Care and Research, Cotignola, Italy., Chang K; Department of Internal Medicine, Cardiology Division, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea., Cleator JH; Division of Cardiology and Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Déry JP; Quebec Heart and Lung Institute, University Laval, Quebec City, QC, Canada., Dridi NP; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Fernandez-Cadenas I; Neurology, Stroke Pharmacogenomics and Genetics Group, Sant Pau Institute of Research, Barcelona, Spain., Fontana P; Department of Biomedical Data Science, Stanford University, Stanford, California, USA.; Geneva Platelet Group and Division of Angiology and Haemostasis, University Hospitals of Geneva, Geneva, Switzerland., Gawaz M; Department of Cardiology and Angiology, University of Tübingen, Tübingen, Germany., Geisler T; Department of Cardiology and Angiology, Medizinische Klinik III, University Hospital Tübingen, Tübingen, Germany., Gensini GF; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Giusti B; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Baltimore, Maryland, USA., Hochholzer W; Department of Cardiology and Angiology II, University Heart Center Freiburg Bad Krozingen, Bad Krozingen, Germany., Holmvang L; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Kim EY; Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, South Korea., Kim HS; Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, South Korea., Marcucci R; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Montaner J; Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Barcelona, Spain., Backman JD; Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA., Pakyz RE; Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA., Roden DM; Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Schaeffeler E; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Tübingen, Germany., Schwab M; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Tübingen, Germany.; Department of Clinical Pharmacology, and Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany., Shin JG; Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, South Korea.; Department of Pharmacology and Pharmacogenomics Research Center, Inje University, Busan Paik Hospital, Busan, South Korea., Siller-Matula JM; Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.; Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Warsaw, Poland., Ten Berg JM; Department of Cardiology, St. Antonius Center for Platelet Function Research, Nieuwegein, The Netherlands., Trenk D; Department of Cardiology and Angiology II, University Heart Center Freiburg Bad Krozingen, Bad Krozingen, Germany.; Department of Clinical Pharmacology, University Heart Centre Freiburg, Bad Krozingen, Germany., Valgimigli M; Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, Bern, Switzerland., Wallace J; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, USA., Wen MS; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou and School of Medicine, Chang Gung University, Taoyuan City, Taiwan., Kubo M; Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan., Lee MTM; Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, USA., Whaley R; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Winter S; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Tübingen, Germany., Klein TE; Department of Biomedical Data Science, Stanford University, Stanford, California, USA.; Department of Medicine, Stanford University, Stanford, California, USA., Shuldiner AR; Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA., Ritchie MD; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Corporate Authors: ICPC Investigators
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 Nov; Vol. 108 (5), pp. 1067-1077. Date of Electronic Publication: 2020 Jul 09.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
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  Data: Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
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