Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy.
Saved in:
| Title: | Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. |
|---|---|
| Authors: | Basher F; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.; Current address: Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA., Dhar P; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Wang X; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Wainwright DA; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Zhang B; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Sosman J; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Ji Z; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, 60628, USA., Wu JD; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu. |
| Source: | Journal of hematology & oncology [J Hematol Oncol] 2020 Jun 09; Vol. 13 (1), pp. 74. Date of Electronic Publication: 2020 Jun 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722 (Electronic) Linking ISSN: 17568722 NLM ISO Abbreviation: J Hematol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1756-8722 |
|---|---|
| DOI: | 10.1186/s13045-020-00896-0 |
