Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy.
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| Title: | Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. |
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| Authors: | Basher F; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.; Current address: Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA., Dhar P; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Wang X; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Wainwright DA; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Zhang B; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Sosman J; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Ji Z; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, 60628, USA., Wu JD; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu. |
| Source: | Journal of hematology & oncology [J Hematol Oncol] 2020 Jun 09; Vol. 13 (1), pp. 74. Date of Electronic Publication: 2020 Jun 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722 (Electronic) Linking ISSN: 17568722 NLM ISO Abbreviation: J Hematol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32517713 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Basher+F%22">Basher F</searchLink>; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.; Current address: Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Dhar+P%22">Dhar P</searchLink>; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Wainwright+DA%22">Wainwright DA</searchLink>; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Sosman+J%22">Sosman J</searchLink>; Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Ji+Z%22">Ji Z</searchLink>; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, 60628, USA.<br /><searchLink fieldCode="AU" term="%22Wu+JD%22">Wu JD</searchLink>; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Driskill Graduate Program in Life Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu.; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jennifer.wu@northwestern.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101468937%22">Journal of hematology & oncology</searchLink> [J Hematol Oncol] 2020 Jun 09; Vol. 13 (1), pp. 74. <i>Date of Electronic Publication: </i>2020 Jun 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101468937 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-8722 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217568722%22">17568722 </searchLink><i>NLM ISO Abbreviation: </i>J Hematol Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32517713 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13045-020-00896-0 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 74 Titles: – TitleFull: Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Basher F – PersonEntity: Name: NameFull: Dhar P – PersonEntity: Name: NameFull: Wang X – PersonEntity: Name: NameFull: Wainwright DA – PersonEntity: Name: NameFull: Zhang B – PersonEntity: Name: NameFull: Sosman J – PersonEntity: Name: NameFull: Ji Z – PersonEntity: Name: NameFull: Wu JD IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 06 Text: 2020 Jun 09 Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1756-8722 Numbering: – Type: volume Value: 13 – Type: issue Value: 1 Titles: – TitleFull: Journal of hematology & oncology Type: main |
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