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Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.

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Title: Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
Authors: Ross TT; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Crowley C; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Kelly KL; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Rinaldi A; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Beebe DA; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Lech MP; Inflammation and Immunology Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Martinez RV; Inflammation and Immunology Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Carvajal-Gonzalez S; Early Clinical Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Boucher M; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Hirenallur-Shanthappa D; Comparative Medicine, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Morin J; Comparative Medicine, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Opsahl AC; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Vargas SR; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Bence KK; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Pfefferkorn JA; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts., Esler WP; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts. Electronic address: William.Esler@Pfizer.com.
Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2020; Vol. 10 (4), pp. 829-851. Date of Electronic Publication: 2020 Jun 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
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  Data: <searchLink fieldCode="AU" term="%22Ross+TT%22">Ross TT</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Crowley+C%22">Crowley C</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kelly+KL%22">Kelly KL</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Rinaldi+A%22">Rinaldi A</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Beebe+DA%22">Beebe DA</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Lech+MP%22">Lech MP</searchLink>; Inflammation and Immunology Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Martinez+RV%22">Martinez RV</searchLink>; Inflammation and Immunology Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Carvajal-Gonzalez+S%22">Carvajal-Gonzalez S</searchLink>; Early Clinical Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Boucher+M%22">Boucher M</searchLink>; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hirenallur-Shanthappa+D%22">Hirenallur-Shanthappa D</searchLink>; Comparative Medicine, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Morin+J%22">Morin J</searchLink>; Comparative Medicine, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Opsahl+AC%22">Opsahl AC</searchLink>; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Vargas+SR%22">Vargas SR</searchLink>; Drug Safety Research and Development, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Bence+KK%22">Bence KK</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pfefferkorn+JA%22">Pfefferkorn JA</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts.<br /><searchLink fieldCode="AU" term="%22Esler+WP%22">Esler WP</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research and Development, Cambridge Massachusetts. Electronic address: William.Esler@Pfizer.com.
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  Data: <searchLink fieldCode="JN" term="%22101648302%22">Cellular and molecular gastroenterology and hepatology</searchLink> [Cell Mol Gastroenterol Hepatol] 2020; Vol. 10 (4), pp. 829-851. <i>Date of Electronic Publication: </i>2020 Jun 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Gastroenterological+Association%22">American Gastroenterological Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101648302 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-345X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222352345X%22">2352345X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Gastroenterol Hepatol <i>Subsets: </i>MEDLINE
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