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p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.

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Title: p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.
Authors: Choi HY; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Siddique HR; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.; Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, 202002, India., Zheng M; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Kou Y; Department of Chemistry and Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA., Yeh DW; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Machida T; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Chen CL; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Uthaya Kumar DB; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.; Department of Genetics and Genomics, and The Jackson Laboratory for Genomic Medicine, University of Connecticut Health, Farmington, 06032, CT, USA., Punj V; Department of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Winer P; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Pita A; Department of Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Sher L; Department of Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Tahara SM; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Ray RB; Saint Louis University, St. Louis, MO, 63103, USA., Liang C; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA., Chen L; Department of Chemistry and Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA., Tsukamoto H; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, 90033, USA.; VA Greater Los Angeles Healthcare System, Los Angeles, 90073, CA, USA., Machida K; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA. keigo.machida@med.usc.edu.; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, 90033, USA. keigo.machida@med.usc.edu.
Source: Nature communications [Nat Commun] 2020 Jun 17; Vol. 11 (1), pp. 3084. Date of Electronic Publication: 2020 Jun 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.
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  Data: <searchLink fieldCode="AU" term="%22Choi+HY%22">Choi HY</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Siddique+HR%22">Siddique HR</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.; Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, 202002, India.<br /><searchLink fieldCode="AU" term="%22Zheng+M%22">Zheng M</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Kou+Y%22">Kou Y</searchLink>; Department of Chemistry and Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+DW%22">Yeh DW</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Machida+T%22">Machida T</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CL%22">Chen CL</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Uthaya+Kumar+DB%22">Uthaya Kumar DB</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.; Department of Genetics and Genomics, and The Jackson Laboratory for Genomic Medicine, University of Connecticut Health, Farmington, 06032, CT, USA.<br /><searchLink fieldCode="AU" term="%22Punj+V%22">Punj V</searchLink>; Department of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Winer+P%22">Winer P</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Pita+A%22">Pita A</searchLink>; Department of Surgery, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Sher+L%22">Sher L</searchLink>; Department of Surgery, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Tahara+SM%22">Tahara SM</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Ray+RB%22">Ray RB</searchLink>; Saint Louis University, St. Louis, MO, 63103, USA.<br /><searchLink fieldCode="AU" term="%22Liang+C%22">Liang C</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Chemistry and Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.<br /><searchLink fieldCode="AU" term="%22Tsukamoto+H%22">Tsukamoto H</searchLink>; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, 90033, USA.; VA Greater Los Angeles Healthcare System, Los Angeles, 90073, CA, USA.<br /><searchLink fieldCode="AU" term="%22Machida+K%22">Machida K</searchLink>; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, 90033, USA. keigo.machida@med.usc.edu.; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, 90033, USA. keigo.machida@med.usc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2020 Jun 17; Vol. 11 (1), pp. 3084. <i>Date of Electronic Publication: </i>2020 Jun 17.
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