A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy.
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| Title: | A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. |
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| Authors: | Venø MT; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Connolly NMC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Su J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Yan Y; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Engel T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Jimenez-Mateos EM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Harder LM; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Pultz D; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Haunsberger SJ; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Pal A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Heller JP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Campbell A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Langa E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Brennan GP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Conboy K; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Richardson A; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Norwood BA; Department of Neuroscience, Expesicor Inc, Kalispell, MT 59901.; Diagnostics Development, FYR Diagnostics, Missoula, MT 59801., Costard LS; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Neubert V; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, 18051, Germany., Del Gallo F; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Salvetti B; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Vangoor VR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Sanz-Rodriguez A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Muilu J; Research and Development, BC Platforms, FI-02130, Espoo, Finland., Fabene PF; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Pasterkamp RJ; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Schorge S; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.; UCL School of Pharmacy, University College London, London, WC1N 1AX, United Kingdom., Andersen JS; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Rosenow F; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Bauer S; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Kjems J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland; dhenshall@rcsi.ie.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15977-15988. Date of Electronic Publication: 2020 Jun 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32581127 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Venø+MT%22">Venø MT</searchLink>; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Reschke+CR%22">Reschke CR</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Morris+G%22">Morris G</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Connolly+NMC%22">Connolly NMC</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Su+J%22">Su J</searchLink>; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Engel+T%22">Engel T</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Jimenez-Mateos+EM%22">Jimenez-Mateos EM</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Harder+LM%22">Harder LM</searchLink>; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Pultz+D%22">Pultz D</searchLink>; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Haunsberger+SJ%22">Haunsberger SJ</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Pal+A%22">Pal A</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Heller+JP%22">Heller JP</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Campbell+A%22">Campbell A</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Langa+E%22">Langa E</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Brennan+GP%22">Brennan GP</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Conboy+K%22">Conboy K</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Richardson+A%22">Richardson A</searchLink>; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Norwood+BA%22">Norwood BA</searchLink>; Department of Neuroscience, Expesicor Inc, Kalispell, MT 59901.; Diagnostics Development, FYR Diagnostics, Missoula, MT 59801.<br /><searchLink fieldCode="AU" term="%22Costard+LS%22">Costard LS</searchLink>; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Neubert+V%22">Neubert V</searchLink>; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, 18051, Germany.<br /><searchLink fieldCode="AU" term="%22Del+Gallo+F%22">Del Gallo F</searchLink>; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Salvetti+B%22">Salvetti B</searchLink>; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Vangoor+VR%22">Vangoor VR</searchLink>; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sanz-Rodriguez+A%22">Sanz-Rodriguez A</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Muilu+J%22">Muilu J</searchLink>; Research and Development, BC Platforms, FI-02130, Espoo, Finland.<br /><searchLink fieldCode="AU" term="%22Fabene+PF%22">Fabene PF</searchLink>; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Pasterkamp+RJ%22">Pasterkamp RJ</searchLink>; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Prehn+JHM%22">Prehn JHM</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.<br /><searchLink fieldCode="AU" term="%22Schorge+S%22">Schorge S</searchLink>; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.; UCL School of Pharmacy, University College London, London, WC1N 1AX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Andersen+JS%22">Andersen JS</searchLink>; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Rosenow+F%22">Rosenow F</searchLink>; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+S%22">Bauer S</searchLink>; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Kjems+J%22">Kjems J</searchLink>; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Henshall+DC%22">Henshall DC</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland; dhenshall@rcsi.ie.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15977-15988. <i>Date of Electronic Publication: </i>2020 Jun 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE |
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