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Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats.

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Title: Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats.
Authors: Prukop T; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen, Germany., Wernick S; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Boussicault L; Pharnext, Issy-Les-Moulineaux, France., Ewers D; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Jäger K; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Adam J; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Winter L; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Quintes S; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Linhoff L; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Barrantes-Freer A; Department of Neuropathology, University Medical Center Leipzig, Leipzig, Germany., Bartl M; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Czesnik D; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Zschüntzsch J; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Schmidt J; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Primas G; Pharnext, Issy-Les-Moulineaux, France., Laffaire J; Pharnext, Issy-Les-Moulineaux, France., Rinaudo P; Pharnext, Issy-Les-Moulineaux, France., Brureau A; Pharnext, Issy-Les-Moulineaux, France., Nabirotchkin S; Pharnext, Issy-Les-Moulineaux, France., Schwab MH; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Nave KA; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Hajj R; Pharnext, Issy-Les-Moulineaux, France., Cohen D; Pharnext, Issy-Les-Moulineaux, France., Sereda MW; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.
Source: Journal of neuroscience research [J Neurosci Res] 2020 Oct; Vol. 98 (10), pp. 1933-1952. Date of Electronic Publication: 2020 Jun 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Interscience Country of Publication: United States NLM ID: 7600111 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4547 (Electronic) Linking ISSN: 03604012 NLM ISO Abbreviation: J Neurosci Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats.
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  Data: <searchLink fieldCode="AU" term="%22Prukop+T%22">Prukop T</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wernick+S%22">Wernick S</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Boussicault+L%22">Boussicault L</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Ewers+D%22">Ewers D</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jäger+K%22">Jäger K</searchLink>; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Adam+J%22">Adam J</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Winter+L%22">Winter L</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Quintes+S%22">Quintes S</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Linhoff+L%22">Linhoff L</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Barrantes-Freer+A%22">Barrantes-Freer A</searchLink>; Department of Neuropathology, University Medical Center Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Bartl+M%22">Bartl M</searchLink>; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Czesnik+D%22">Czesnik D</searchLink>; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Zschüntzsch+J%22">Zschüntzsch J</searchLink>; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+J%22">Schmidt J</searchLink>; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Primas+G%22">Primas G</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Laffaire+J%22">Laffaire J</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Rinaudo+P%22">Rinaudo P</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Brureau+A%22">Brureau A</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Nabirotchkin+S%22">Nabirotchkin S</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Schwab+MH%22">Schwab MH</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Nave+KA%22">Nave KA</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hajj+R%22">Hajj R</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Cohen+D%22">Cohen D</searchLink>; Pharnext, Issy-Les-Moulineaux, France.<br /><searchLink fieldCode="AU" term="%22Sereda+MW%22">Sereda MW</searchLink>; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.
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