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Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.

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Title: Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
Authors: Zhai L; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Bell A; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Ladomersky E; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Lauing KL; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Bollu L; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Sosman JA; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States., Zhang B; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Wu JD; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Miller SD; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Meeks JJ; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Lukas RV; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Wyatt E; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Transgenic and Targeted Mutagenesis Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Doglio L; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Transgenic and Targeted Mutagenesis Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Schiltz GE; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Center for Molecular Innovation and Drug Discovery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., McCusker RH; Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States., Wainwright DA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Source: Frontiers in immunology [Front Immunol] 2020 Jun 16; Vol. 11, pp. 1185. Date of Electronic Publication: 2020 Jun 16 (Print Publication: 2020).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zhai+L%22">Zhai L</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Bell+A%22">Bell A</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Ladomersky+E%22">Ladomersky E</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Lauing+KL%22">Lauing KL</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Bollu+L%22">Bollu L</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Sosman+JA%22">Sosman JA</searchLink>; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Wu+JD%22">Wu JD</searchLink>; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Miller+SD%22">Miller SD</searchLink>; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Meeks+JJ%22">Meeks JJ</searchLink>; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Lukas+RV%22">Lukas RV</searchLink>; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Wyatt+E%22">Wyatt E</searchLink>; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Transgenic and Targeted Mutagenesis Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Doglio+L%22">Doglio L</searchLink>; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Transgenic and Targeted Mutagenesis Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Schiltz+GE%22">Schiltz GE</searchLink>; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Center for Molecular Innovation and Drug Discovery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22McCusker+RH%22">McCusker RH</searchLink>; Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States.<br /><searchLink fieldCode="AU" term="%22Wainwright+DA%22">Wainwright DA</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, United States.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2020 Jun 16; Vol. 11, pp. 1185. <i>Date of Electronic Publication: </i>2020 Jun 16 (<i>Print Publication: </i>2020).
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        Value: 10.3389/fimmu.2020.01185
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