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The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.

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Title: The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
Authors: Krebs A; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; Konstanz Research School Chemical Biology, University of Konstanz, 78457, Konstanz, Germany., van Vugt-Lussenburg BMA; BioDetection Systems BV, Science Park 406, 1098 XH, Amsterdam, The Netherlands., Waldmann T; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; trenzyme GmbH, Byk-Gulden-Str. 2, 78467, Konstanz, Germany., Albrecht W; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany., Boei J; Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands., Ter Braak B; Division of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands., Brajnik M; Edelweiss Connect GmbH, Technology Park Basel, Hochbergerstrasse 60C, 4057, Basel, Switzerland., Braunbeck T; Aquatic Ecology and Toxicology Group, Center for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, 69120, Heidelberg, Germany., Brecklinghaus T; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany., Busquet F; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany., Dinnyes A; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary., Dokler J; Edelweiss Connect GmbH, Technology Park Basel, Hochbergerstrasse 60C, 4057, Basel, Switzerland., Dolde X; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany., Exner TE; Edelweiss Connect GmbH, Technology Park Basel, Hochbergerstrasse 60C, 4057, Basel, Switzerland., Fisher C; Simcyp Division, Certara UK Limited, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK., Fluri D; InSphero AG, Wagistrasse 27, 8952, Schlieren, Switzerland., Forsby A; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden.; Department of Biochemistry and Biophysics, Stockholm University, 10691, Stockholm, Sweden., Hengstler JG; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany., Holzer AK; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany., Janstova Z; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary., Jennings P; Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands., Kisitu J; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; Konstanz Research School Chemical Biology, University of Konstanz, 78457, Konstanz, Germany., Kobolak J; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary., Kumar M; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute Leuven, KU Leuven, O&N IV Herestraat 49, 3000, Leuven, Belgium., Limonciel A; Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands., Lundqvist J; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden.; Department of Biochemistry and Biophysics, Stockholm University, 10691, Stockholm, Sweden., Mihalik B; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary., Moritz W; InSphero AG, Wagistrasse 27, 8952, Schlieren, Switzerland., Pallocca G; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany., Ulloa APC; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden., Pastor M; Department of Experimental and Health Sciences, Research Programme on Biomedical Informatics (GRIB), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Pompeu Fabra, 08003, Barcelona, Spain., Rovida C; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany., Sarkans U; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK., Schimming JP; Leiden Academic Center for Drug Research, LACDR/Toxicology, Leiden University, PO Box 9500, 2300 RA, Leiden, The Netherlands., Schmidt BZ; Switch Laboratory, Department of Cellular and Molecular Medicine, VIB-KU Leuven Center for Brain and Disease Research, KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Stöber R; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany., Strassfeld T; InSphero AG, Wagistrasse 27, 8952, Schlieren, Switzerland., van de Water B; Leiden Academic Center for Drug Research, LACDR/Toxicology, Leiden University, PO Box 9500, 2300 RA, Leiden, The Netherlands., Wilmes A; Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands., van der Burg B; BioDetection Systems BV, Science Park 406, 1098 XH, Amsterdam, The Netherlands., Verfaillie CM; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute Leuven, KU Leuven, O&N IV Herestraat 49, 3000, Leuven, Belgium., von Hellfeld R; Aquatic Ecology and Toxicology Group, Center for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, 69120, Heidelberg, Germany., Vrieling H; Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands., Vrijenhoek NG; Leiden Academic Center for Drug Research, LACDR/Toxicology, Leiden University, PO Box 9500, 2300 RA, Leiden, The Netherlands., Leist M; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany. marcel.leist@uni-konstanz.de.; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany. marcel.leist@uni-konstanz.de.
Source: Archives of toxicology [Arch Toxicol] 2020 Jul; Vol. 94 (7), pp. 2435-2461. Date of Electronic Publication: 2020 Jul 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
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  Data: <searchLink fieldCode="AU" term="%22Krebs+A%22">Krebs A</searchLink>; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; Konstanz Research School Chemical Biology, University of Konstanz, 78457, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22van+Vugt-Lussenburg+BMA%22">van Vugt-Lussenburg BMA</searchLink>; BioDetection Systems BV, Science Park 406, 1098 XH, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Waldmann+T%22">Waldmann T</searchLink>; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; trenzyme GmbH, Byk-Gulden-Str. 2, 78467, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Albrecht+W%22">Albrecht W</searchLink>; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Boei+J%22">Boei J</searchLink>; Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ter+Braak+B%22">Ter Braak B</searchLink>; Division of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Brajnik+M%22">Brajnik M</searchLink>; Edelweiss Connect GmbH, Technology Park Basel, Hochbergerstrasse 60C, 4057, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Braunbeck+T%22">Braunbeck T</searchLink>; Aquatic Ecology and Toxicology Group, Center for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Brecklinghaus+T%22">Brecklinghaus T</searchLink>; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Busquet+F%22">Busquet F</searchLink>; 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InSphero AG, Wagistrasse 27, 8952, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forsby+A%22">Forsby A</searchLink>; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden.; Department of Biochemistry and Biophysics, Stockholm University, 10691, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hengstler+JG%22">Hengstler JG</searchLink>; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Holzer+AK%22">Holzer AK</searchLink>; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Janstova+Z%22">Janstova Z</searchLink>; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary.<br /><searchLink fieldCode="AU" term="%22Jennings+P%22">Jennings P</searchLink>; Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kisitu+J%22">Kisitu J</searchLink>; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, Universitaetsstr. 10, 78457, Konstanz, Germany.; Konstanz Research School Chemical Biology, University of Konstanz, 78457, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Kobolak+J%22">Kobolak J</searchLink>; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary.<br /><searchLink fieldCode="AU" term="%22Kumar+M%22">Kumar M</searchLink>; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute Leuven, KU Leuven, O&N IV Herestraat 49, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Limonciel+A%22">Limonciel A</searchLink>; Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lundqvist+J%22">Lundqvist J</searchLink>; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden.; Department of Biochemistry and Biophysics, Stockholm University, 10691, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Mihalik+B%22">Mihalik B</searchLink>; BioTalentum Ltd., Aulich Lajos str. 26, Gödöllő, 2100, Hungary.<br /><searchLink fieldCode="AU" term="%22Moritz+W%22">Moritz W</searchLink>; InSphero AG, Wagistrasse 27, 8952, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pallocca+G%22">Pallocca G</searchLink>; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Ulloa+APC%22">Ulloa APC</searchLink>; Unit of Toxicology Sciences, Swedish Toxicology Sciences Research Center (Swetox), Karolinska Institutet, Forskargatan 20, 151 36, Södertälje, Sweden.<br /><searchLink fieldCode="AU" term="%22Pastor+M%22">Pastor M</searchLink>; Department of Experimental and Health Sciences, Research Programme on Biomedical Informatics (GRIB), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Pompeu Fabra, 08003, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rovida+C%22">Rovida C</searchLink>; CAAT Europe, University of Konstanz, Steinbeis SU-1866, 78457, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Sarkans+U%22">Sarkans U</searchLink>; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Schimming+JP%22">Schimming JP</searchLink>; Leiden Academic Center for Drug Research, LACDR/Toxicology, Leiden University, PO Box 9500, 2300 RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schmidt+BZ%22">Schmidt BZ</searchLink>; Switch Laboratory, Department of Cellular and Molecular Medicine, VIB-KU Leuven Center for Brain and Disease Research, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Stöber+R%22">Stöber R</searchLink>; Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystraße 67, 44139, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Strassfeld+T%22">Strassfeld T</searchLink>; 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      – PersonEntity:
          Name:
            NameFull: von Hellfeld R
      – PersonEntity:
          Name:
            NameFull: Vrieling H
      – PersonEntity:
          Name:
            NameFull: Vrijenhoek NG
      – PersonEntity:
          Name:
            NameFull: Leist M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2020 Jul
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 1432-0738
          Numbering:
            – Type: volume
              Value: 94
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Archives of toxicology
              Type: main
ResultId 1