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The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells.

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Title: The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells.
Authors: Maharaj K; Department of Malignant Hematology.; Department of Immunology, and.; Department of Cancer Biology PhD Program, University of South Florida and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Powers JJ; Department of Immunology, and., Achille A; Department of Immunology, and., Mediavilla-Varela M; Department of Malignant Hematology.; Department of Immunology, and., Gamal W; Department of Immunology, and.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL., Burger KL; Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Fonseca R; Department of Immunology, and., Jiang K; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Miskin HP; TG Therapeutics, Inc., New York, NY., Maryanski D; TG Therapeutics, Inc., New York, NY., Monastyrskyi A; Department of Drug Discovery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and., Duckett DR; Department of Drug Discovery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and., Roush WR; Department of Molecular Medicine, The Scripps Research Institute, Scripps Florida, Jupiter, FL., Cleveland JL; Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Sahakian E; Department of Malignant Hematology.; Department of Immunology, and., Pinilla-Ibarz J; Department of Malignant Hematology.; Department of Immunology, and.
Source: Blood advances [Blood Adv] 2020 Jul 14; Vol. 4 (13), pp. 3072-3084.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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        Value: 10.1182/bloodadvances.2020001800
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              Text: 2020 Jul 14
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