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Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.

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Title: Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.
Authors: McLaughlin LJ; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201., Stojanovic L; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201., Kogan AA; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201., Rutherford JL; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201., Choi EY; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201., Yen RC; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231., Xia L; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231., Zou Y; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201., Lapidus RG; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201., Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu., Topper MJ; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu., Rassool FV; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 28; Vol. 117 (30), pp. 17785-17795. Date of Electronic Publication: 2020 Jul 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.
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  Data: <searchLink fieldCode="AU" term="%22McLaughlin+LJ%22">McLaughlin LJ</searchLink>; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Stojanovic+L%22">Stojanovic L</searchLink>; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Kogan+AA%22">Kogan AA</searchLink>; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Rutherford+JL%22">Rutherford JL</searchLink>; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Choi+EY%22">Choi EY</searchLink>; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Yen+RC%22">Yen RC</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231.<br /><searchLink fieldCode="AU" term="%22Xia+L%22">Xia L</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231.<br /><searchLink fieldCode="AU" term="%22Zou+Y%22">Zou Y</searchLink>; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Lapidus+RG%22">Lapidus RG</searchLink>; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu.<br /><searchLink fieldCode="AU" term="%22Topper+MJ%22">Topper MJ</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu.<br /><searchLink fieldCode="AU" term="%22Rassool+FV%22">Rassool FV</searchLink>; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201; sbaylin@jhmi.edu mtopper1@jhmi.edu frassool@som.umaryland.edu.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201.
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