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Reduced Rivaroxaban Dose Versus Dual Antiplatelet Therapy After Left Atrial Appendage Closure: ADRIFT a Randomized Pilot Study.

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Title: Reduced Rivaroxaban Dose Versus Dual Antiplatelet Therapy After Left Atrial Appendage Closure: ADRIFT a Randomized Pilot Study.
Authors: Duthoit G; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Silvain J; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Marijon E; European Georges Pompidou Hospital, APHP; Paris Descartes University, INSERM U 970, France (E.M., C.S.)., Ducrocq G; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.)., Lepillier A; Department of Cardiology, Centre Cardiologique du Nord, Saint-Denis, France (A.L., D.A.)., Frere C; Sorbonne Université, Department of Haematology Biologic, APHP Pitié-Salpêtrière Hospital; INSERM UMRS 1166, Institute of Cardiometabolism And Nutrition, Paris, France (C.F., I.M.-T.)., Dimby SF; Unité de Recherche Clinique, ACTION Study Group, Hôpital Fernand Widal (AP-HP), SAMM - Statistique, Analyse et Modélisation Multidisciplinaire EA 4543, Université Paris 1 Panthéon Sorbonne, France (S.-F.D., E.V.)., Popovic B; Université de Lorraine, Département de Cardiologie, Centre Hospitalier Universitaire Brabois, Nancy, France (B.P.)., Lellouche N; Département de Cardiologie, CHU Henri Mondor, Créteil, France (N.L.)., Martin-Toutain I; Sorbonne Université, Department of Haematology Biologic, APHP Pitié-Salpêtrière Hospital; INSERM UMRS 1166, Institute of Cardiometabolism And Nutrition, Paris, France (C.F., I.M.-T.)., Spaulding C; European Georges Pompidou Hospital, APHP; Paris Descartes University, INSERM U 970, France (E.M., C.S.)., Brochet E; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.)., Attias D; Department of Cardiology, Centre Cardiologique du Nord, Saint-Denis, France (A.L., D.A.)., Mansourati J; Département de Cardiologie, CHRU Brest, Université de Bretagne Occidentale, EA 4324 (J.M.)., Lorgis L; Department of Cardiology, Laboratory of Cerebro-Vascular Pathophysiology and epidemiology (PEC2) EA 7460, University of Burgundy, Dijon, France (L.L.)., Klug D; Univ. Lille CHU Lille, F-59000 Lille, France (D.K.)., Zannad N; Département de Cardiologie, CHR Metz-Thionville, France (N.Z.)., Hauguel-Moreau M; Université de Versailles-Saint Quentin, Department of Cardiology, Ambroise Paré Hospital (AP-HP), INSERM U-1018, Boulogne, France (M.H.-M.)., Braik N; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Deltour S; Sorbonne Université, Urgences Cerebro-Vasculaires Pitié-Salpêtrière Hospital (AP-HP), INSERM UMR U-942, Paris, France (S.D.)., Ceccaldi A; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Wang H; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China (H.W.)., Hammoudi N; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Brugier D; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.)., Vicaut E; Unité de Recherche Clinique, ACTION Study Group, Hôpital Fernand Widal (AP-HP), SAMM - Statistique, Analyse et Modélisation Multidisciplinaire EA 4543, Université Paris 1 Panthéon Sorbonne, France (S.-F.D., E.V.)., Juliard JM; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.)., Montalescot G; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).
Source: Circulation. Cardiovascular interventions [Circ Cardiovasc Interv] 2020 Jul; Vol. 13 (7), pp. e008481. Date of Electronic Publication: 2020 Jul 17.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101499602 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-7632 (Electronic) Linking ISSN: 19417640 NLM ISO Abbreviation: Circ Cardiovasc Interv Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Reduced Rivaroxaban Dose Versus Dual Antiplatelet Therapy After Left Atrial Appendage Closure: ADRIFT a Randomized Pilot Study.
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  Data: <searchLink fieldCode="AU" term="%22Duthoit+G%22">Duthoit G</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Silvain+J%22">Silvain J</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Marijon+E%22">Marijon E</searchLink>; European Georges Pompidou Hospital, APHP; Paris Descartes University, INSERM U 970, France (E.M., C.S.).<br /><searchLink fieldCode="AU" term="%22Ducrocq+G%22">Ducrocq G</searchLink>; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.).<br /><searchLink fieldCode="AU" term="%22Lepillier+A%22">Lepillier A</searchLink>; Department of Cardiology, Centre Cardiologique du Nord, Saint-Denis, France (A.L., D.A.).<br /><searchLink fieldCode="AU" term="%22Frere+C%22">Frere C</searchLink>; Sorbonne Université, Department of Haematology Biologic, APHP Pitié-Salpêtrière Hospital; INSERM UMRS 1166, Institute of Cardiometabolism And Nutrition, Paris, France (C.F., I.M.-T.).<br /><searchLink fieldCode="AU" term="%22Dimby+SF%22">Dimby SF</searchLink>; Unité de Recherche Clinique, ACTION Study Group, Hôpital Fernand Widal (AP-HP), SAMM - Statistique, Analyse et Modélisation Multidisciplinaire EA 4543, Université Paris 1 Panthéon Sorbonne, France (S.-F.D., E.V.).<br /><searchLink fieldCode="AU" term="%22Popovic+B%22">Popovic B</searchLink>; Université de Lorraine, Département de Cardiologie, Centre Hospitalier Universitaire Brabois, Nancy, France (B.P.).<br /><searchLink fieldCode="AU" term="%22Lellouche+N%22">Lellouche N</searchLink>; Département de Cardiologie, CHU Henri Mondor, Créteil, France (N.L.).<br /><searchLink fieldCode="AU" term="%22Martin-Toutain+I%22">Martin-Toutain I</searchLink>; Sorbonne Université, Department of Haematology Biologic, APHP Pitié-Salpêtrière Hospital; INSERM UMRS 1166, Institute of Cardiometabolism And Nutrition, Paris, France (C.F., I.M.-T.).<br /><searchLink fieldCode="AU" term="%22Spaulding+C%22">Spaulding C</searchLink>; European Georges Pompidou Hospital, APHP; Paris Descartes University, INSERM U 970, France (E.M., C.S.).<br /><searchLink fieldCode="AU" term="%22Brochet+E%22">Brochet E</searchLink>; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.).<br /><searchLink fieldCode="AU" term="%22Attias+D%22">Attias D</searchLink>; Department of Cardiology, Centre Cardiologique du Nord, Saint-Denis, France (A.L., D.A.).<br /><searchLink fieldCode="AU" term="%22Mansourati+J%22">Mansourati J</searchLink>; Département de Cardiologie, CHRU Brest, Université de Bretagne Occidentale, EA 4324 (J.M.).<br /><searchLink fieldCode="AU" term="%22Lorgis+L%22">Lorgis L</searchLink>; Department of Cardiology, Laboratory of Cerebro-Vascular Pathophysiology and epidemiology (PEC2) EA 7460, University of Burgundy, Dijon, France (L.L.).<br /><searchLink fieldCode="AU" term="%22Klug+D%22">Klug D</searchLink>; Univ. Lille CHU Lille, F-59000 Lille, France (D.K.).<br /><searchLink fieldCode="AU" term="%22Zannad+N%22">Zannad N</searchLink>; Département de Cardiologie, CHR Metz-Thionville, France (N.Z.).<br /><searchLink fieldCode="AU" term="%22Hauguel-Moreau+M%22">Hauguel-Moreau M</searchLink>; Université de Versailles-Saint Quentin, Department of Cardiology, Ambroise Paré Hospital (AP-HP), INSERM U-1018, Boulogne, France (M.H.-M.).<br /><searchLink fieldCode="AU" term="%22Braik+N%22">Braik N</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Deltour+S%22">Deltour S</searchLink>; Sorbonne Université, Urgences Cerebro-Vasculaires Pitié-Salpêtrière Hospital (AP-HP), INSERM UMR U-942, Paris, France (S.D.).<br /><searchLink fieldCode="AU" term="%22Ceccaldi+A%22">Ceccaldi A</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China (H.W.).<br /><searchLink fieldCode="AU" term="%22Hammoudi+N%22">Hammoudi N</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Brugier+D%22">Brugier D</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).<br /><searchLink fieldCode="AU" term="%22Vicaut+E%22">Vicaut E</searchLink>; Unité de Recherche Clinique, ACTION Study Group, Hôpital Fernand Widal (AP-HP), SAMM - Statistique, Analyse et Modélisation Multidisciplinaire EA 4543, Université Paris 1 Panthéon Sorbonne, France (S.-F.D., E.V.).<br /><searchLink fieldCode="AU" term="%22Juliard+JM%22">Juliard JM</searchLink>; Département de Cardiologie, Hôpital Bichat, AP-HP, Université Paris-Diderot, Inserm U1148, France (G.D., E.B., J.-M.J.).<br /><searchLink fieldCode="AU" term="%22Montalescot+G%22">Montalescot G</searchLink>; Sorbonne Université, ACTION Study Group (Allies in Cardiovascular Trials, Initiatives and Organized Networks), INSERM UMRS1166, ICAN, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France (G.D., J.S., N.B., A.C., N.H., D.B., G.M.).
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