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Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.

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Title: Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.
Authors: Chelliah V; Certara UK Ltd., Sheffield, UK., Lazarou G; Certara UK Ltd., Sheffield, UK., Bhatnagar S; Abbvie Inc., North Chicago, Illinois, USA., Gibbs JP; Abbvie Inc., North Chicago, Illinois, USA., Nijsen M; Abbvie Inc., North Chicago, Illinois, USA., Ray A; Abbvie Inc., North Chicago, Illinois, USA., Stoll B; Abbvie Inc., North Chicago, Illinois, USA., Thompson RA; Abbvie Inc., North Chicago, Illinois, USA., Gulati A; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Soukharev S; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Yamada A; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Weddell J; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Sayama H; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Oishi M; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Northbrook, Illinois, USA.; Astellas Pharma Global Development Inc./Astellas Pharma Inc., Tokyo or Tsukuba-shi, Japan., Wittemer-Rump S; Bayer AG, Leverkusen, Germany., Patel C; Bayer AG, Leverkusen, Germany., Niederalt C; Bayer AG, Leverkusen, Germany., Burghaus R; Bayer AG, Leverkusen, Germany., Scheerans C; Bayer AG, Leverkusen, Germany., Lippert J; Bayer AG, Leverkusen, Germany., Kabilan S; EMD Serono, Merck KGaA, Billerica, Massachusetts, USA., Kareva I; EMD Serono, Merck KGaA, Billerica, Massachusetts, USA., Belousova N; EMD Serono, Merck KGaA, Billerica, Massachusetts, USA., Rolfe A; EMD Serono, Merck KGaA, Billerica, Massachusetts, USA., Zutshi A; EMD Serono, Merck KGaA, Billerica, Massachusetts, USA., Chenel M; Servier, Suresnes, France., Venezia F; Servier, Suresnes, France., Fouliard S; Servier, Suresnes, France., Oberwittler H; Servier, Suresnes, France., Scholer-Dahirel A; Servier, Suresnes, France., Lelievre H; Servier, Suresnes, France., Bottino D; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Collins SC; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Nguyen HQ; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Wang H; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Yoneyama T; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Zhu AZX; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., van der Graaf PH; Certara UK Ltd., Sheffield, UK., Kierzek AM; Certara UK Ltd., Sheffield, UK.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Mar; Vol. 109 (3), pp. 605-618. Date of Electronic Publication: 2020 Aug 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1532-6535
DOI:10.1002/cpt.1987