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Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.

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Title: Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Authors: Pasciuto E; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Burton OT; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Roca CP; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Lagou V; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Rajan WD; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Theys T; Department of Neurosurgery, UZ Leuven, Leuven 3000, Belgium., Mancuso R; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium., Tito RY; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; VIB-KU Leuven Center for Microbiology, VIB, Leuven 3000, Belgium., Kouser L; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Callaerts-Vegh Z; Department of Brain and Cognition, KU Leuven-University of Leuven, Leuven 3000, Belgium., de la Fuente AG; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK., Prezzemolo T; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Mascali LG; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Brajic A; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Whyte CE; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Yshii L; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Martinez-Muriana A; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium., Naughton M; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK., Young A; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK., Moudra A; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Lemaitre P; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium., Poovathingal S; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium., Raes J; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; VIB-KU Leuven Center for Microbiology, VIB, Leuven 3000, Belgium., De Strooper B; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium; Dementia Research Institute, University College London, London WC1E 6BT, UK., Fitzgerald DC; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK., Dooley J; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK., Liston A; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK. Electronic address: adrian.liston@babraham.ac.uk.
Source: Cell [Cell] 2020 Aug 06; Vol. 182 (3), pp. 625-640.e24. Date of Electronic Publication: 2020 Jul 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
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  Data: <searchLink fieldCode="AU" term="%22Pasciuto+E%22">Pasciuto E</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Burton+OT%22">Burton OT</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Roca+CP%22">Roca CP</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Lagou+V%22">Lagou V</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Rajan+WD%22">Rajan WD</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Theys+T%22">Theys T</searchLink>; Department of Neurosurgery, UZ Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Mancuso+R%22">Mancuso R</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Tito+RY%22">Tito RY</searchLink>; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; VIB-KU Leuven Center for Microbiology, VIB, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Kouser+L%22">Kouser L</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Callaerts-Vegh+Z%22">Callaerts-Vegh Z</searchLink>; Department of Brain and Cognition, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22de+la+Fuente+AG%22">de la Fuente AG</searchLink>; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK.<br /><searchLink fieldCode="AU" term="%22Prezzemolo+T%22">Prezzemolo T</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Mascali+LG%22">Mascali LG</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Brajic+A%22">Brajic A</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Whyte+CE%22">Whyte CE</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Yshii+L%22">Yshii L</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Martinez-Muriana+A%22">Martinez-Muriana A</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Naughton+M%22">Naughton M</searchLink>; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK.<br /><searchLink fieldCode="AU" term="%22Young+A%22">Young A</searchLink>; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK.<br /><searchLink fieldCode="AU" term="%22Moudra+A%22">Moudra A</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Lemaitre+P%22">Lemaitre P</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Poovathingal+S%22">Poovathingal S</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Raes+J%22">Raes J</searchLink>; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; VIB-KU Leuven Center for Microbiology, VIB, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Strooper+B%22">De Strooper B</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven-University of Leuven, Leuven 3000, Belgium; Dementia Research Institute, University College London, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+DC%22">Fitzgerald DC</searchLink>; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast BT7 1NN, UK.<br /><searchLink fieldCode="AU" term="%22Dooley+J%22">Dooley J</searchLink>; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Liston+A%22">Liston A</searchLink>; VIB Center for Brain and Disease Research, VIB, Leuven 3000, Belgium; Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven 3000, Belgium; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK. Electronic address: adrian.liston@babraham.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2020 Aug 06; Vol. 182 (3), pp. 625-640.e24. <i>Date of Electronic Publication: </i>2020 Jul 22.
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