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Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.

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Title: Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Authors: Gleitz HFE; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Dugourd AJF; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Institute of Computational Biomedicine, Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Heidelberg, Germany., Leimkühler NB; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Snoeren IAM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Fuchs SNR; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Menzel S; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany., Ziegler S; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany., Kröger N; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Triviai I; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Büsche G; Institute of Pathology, Hannover Medical School, Hannover, Germany., Kreipe H; Institute of Pathology, Hannover Medical School, Hannover, Germany., Banjanin B; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Pritchard JE; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands., Hoogenboezem R; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands., Bindels EM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands., Schumacher N; Institute of Biochemistry, University of Kiel, Kiel, Germany., Rose-John S; Institute of Biochemistry, University of Kiel, Kiel, Germany., Elf S; Ben May Department, University of Chicago, Chicago, IL., Saez-Rodriguez J; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Institute of Computational Biomedicine, Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Heidelberg, Germany., Kramann R; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands., Schneider RK; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany; and.; Institute for Biomedical Engineering, Department of Cell Biology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.
Source: Blood [Blood] 2020 Oct 29; Vol. 136 (18), pp. 2051-2064.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
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  Data: <searchLink fieldCode="AU" term="%22Gleitz+HFE%22">Gleitz HFE</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dugourd+AJF%22">Dugourd AJF</searchLink>; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Institute of Computational Biomedicine, Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Leimkühler+NB%22">Leimkühler NB</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snoeren+IAM%22">Snoeren IAM</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fuchs+SNR%22">Fuchs SNR</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Menzel+S%22">Menzel S</searchLink>; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Ziegler+S%22">Ziegler S</searchLink>; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kröger+N%22">Kröger N</searchLink>; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Triviai+I%22">Triviai I</searchLink>; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Büsche+G%22">Büsche G</searchLink>; Institute of Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Kreipe+H%22">Kreipe H</searchLink>; Institute of Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Banjanin+B%22">Banjanin B</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pritchard+JE%22">Pritchard JE</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hoogenboezem+R%22">Hoogenboezem R</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bindels+EM%22">Bindels EM</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schumacher+N%22">Schumacher N</searchLink>; Institute of Biochemistry, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Rose-John+S%22">Rose-John S</searchLink>; Institute of Biochemistry, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Elf+S%22">Elf S</searchLink>; Ben May Department, University of Chicago, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Saez-Rodriguez+J%22">Saez-Rodriguez J</searchLink>; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Institute of Computational Biomedicine, Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kramann+R%22">Kramann R</searchLink>; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schneider+RK%22">Schneider RK</searchLink>; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands.; Oncode Institute, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany; and.; Institute for Biomedical Engineering, Department of Cell Biology, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2020 Oct 29; Vol. 136 (18), pp. 2051-2064.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
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