Structural insights into differences in G protein activation by family A and family B GPCRs.

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Title: Structural insights into differences in G protein activation by family A and family B GPCRs.
Authors: Hilger D; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA., Kumar KK; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA., Hu H; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.; Department of Structural Biology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA., Pedersen MF; Zealand Pharma A/S, Sydmarken 11, Søborg 2860, Denmark., O'Brien ES; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA., Giehm L; Zealand Pharma A/S, Sydmarken 11, Søborg 2860, Denmark., Jennings C; Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Eskici G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.; Department of Structural Biology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan., Lerch M; Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Mathiesen JM; Zealand Pharma A/S, Sydmarken 11, Søborg 2860, Denmark. jmm@zealandpharma.com yiorgo@stanford.edu kobilka@stanford.edu., Skiniotis G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. jmm@zealandpharma.com yiorgo@stanford.edu kobilka@stanford.edu.; Department of Structural Biology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.; Department of Photon Science, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA., Kobilka BK; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. jmm@zealandpharma.com yiorgo@stanford.edu kobilka@stanford.edu.
Source: Science (New York, N.Y.) [Science] 2020 Jul 31; Vol. 369 (6503).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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              Text: 2020 Jul 31
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