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A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer.

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Title: A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer.
Authors: Murphy AG; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Zahurak M; Department of Oncology, Biostatistics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Shah M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Weekes CD; University of Colorado, Boulder, Colorado, USA., Hansen A; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Siu LL; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Spreafico A; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., LoConte N; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, USA., Anders NM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Analytical Pharmacology Core, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA., Miles T; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rudek MA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Analytical Pharmacology Core, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Doyle LA; Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland, USA., Nelkin B; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Maitra A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Azad NS; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Corporate Authors: ETCTN-9231 Study Team
Source: Clinical and translational science [Clin Transl Sci] 2020 Nov; Vol. 13 (6), pp. 1178-1188. Date of Electronic Publication: 2020 Aug 01.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Murphy+AG%22">Murphy AG</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Zahurak+M%22">Zahurak M</searchLink>; Department of Oncology, Biostatistics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Shah+M%22">Shah M</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Weekes+CD%22">Weekes CD</searchLink>; University of Colorado, Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+A%22">Hansen A</searchLink>; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Siu+LL%22">Siu LL</searchLink>; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Spreafico+A%22">Spreafico A</searchLink>; Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22LoConte+N%22">LoConte N</searchLink>; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Anders+NM%22">Anders NM</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Analytical Pharmacology Core, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Miles+T%22">Miles T</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Rudek+MA%22">Rudek MA</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Analytical Pharmacology Core, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Doyle+LA%22">Doyle LA</searchLink>; Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Nelkin+B%22">Nelkin B</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Maitra+A%22">Maitra A</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Azad+NS%22">Azad NS</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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