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Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.

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Title: Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Authors: Newberry RW; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States., Arhar T; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94143, United States., Costello J; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Hartoularos GC; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Maxwell AM; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94143, United States., Naing ZZC; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Pittman M; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Reddy NR; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Schwarz DMC; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94143, United States., Wassarman DR; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94143, United States., Wu TS; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94143, United States., Barrero D; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Caggiano C; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Catching A; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Cavazos TB; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Estes LS; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Faust B; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Fink EA; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Goldman MA; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Gomez YK; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Gordon MG; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Gunsalus LM; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Hoppe N; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Jaime-Garza M; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Johnson MC; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Jones MG; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Kung AF; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Lopez KE; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Lumpe J; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Martyn C; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., McCarthy EE; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Miller-Vedam LE; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Navarro EJ; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Palar A; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Pellegrino J; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Saylor W; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Stephens CA; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Strickland J; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Torosyan H; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Wankowicz SA; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Wong DR; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Wong G; Integrative Program in Quantitative Biology, University of California, San Francisco, California 94143, United States., Redding S; Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, United States., Chow ED; Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, United States., DeGrado WF; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States., Kampmann M; Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, United States.; Institute for Neurodegenerative Disease, University of California, San Francisco, California 94143, United States.; Chan Zuckerberg Biohub, San Francisco, California 94158, United States.
Source: ACS chemical biology [ACS Chem Biol] 2020 Aug 21; Vol. 15 (8), pp. 2137-2153. Date of Electronic Publication: 2020 Aug 12.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
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